Results 111 to 120 of about 37,485,858 (384)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The effect of community resilience and disaster risk management cycle stages on morbi-mortality following floods: an empirical assessment [PDF]
Natural Hazards and Earth System SciencesPractice and policy have emphasized the need for building resilience to climate-related events in a further warming world. Scholarship has studied resilience largely in terms of process, latent capacity informing vulnerability, or the outcome of risk ...
R. Guimaraes +4 more
doaj +1 more source
Improving parallel program performance using critical path analysis [PDF]
, 1989 A programming tool that performs analysis of critical paths for parallel programs has been developed. This tool determines the critical path for the program as scheduled onto a parallel computer with P processing elements, the critical path for the ...
Bic, Lubomir +2 more
core
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Uncertainty in soil data can outweigh climate impact signals in global crop yield simulations
Nature Communications, 2016 Global gridded crop models are increasingly used to assess climate change impacts on food production. Here, the authors assess crop yield uncertainty associated with soil data input, reporting that soil type strongly influences yield estimates, and may ...
Christian Folberth +6 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
An application layer with protocol-based java smart contract verification
Frontiers in Computer ScienceSmart contracts are software that runs in blockchain and expresses the rules of an agreement between parties. An incorrect smart contract might allow blockchain users to violate its rules and even jeopardize its expected security.
Luca Olivieri +2 more
doaj +1 more source
Understanding the origin of Paris Agreement emission uncertainties
Nature Communications, 2017 The pledges put forward by each country to meet the goals of the Paris Agreement are ambiguous. Rogeljet al. quantify the uncertainty arising from the interpretation of these pledges and find that by 2030 global emissions can vary by −10% to +20% around ...
Joeri Rogelj +5 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source