Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Program Evaluation for Graduate Medical Education: Practical Approaches From the Reimagining Residency Evaluation Community of Practice. [PDF]
Richardson J +11 more
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Cooking with confidence for autistic youth: outcomes from a pilot program evaluation model. [PDF]
Wong MY +9 more
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Who's at the Table? A Scoping Review of Stakeholder Engagement in Medical Education Program Evaluation. [PDF]
Macabrey J, Wuest LL, Buetti D.
europepmc +1 more source
Application of an Innovative Methodology to Build Infrastructure for Digital Transformation of Health Systems: Developmental Program Evaluation. [PDF]
Buchan MC, Katapally TR, Bhawra J.
europepmc +1 more source
Program Evaluation of Community Case Management with Reactive Test and Treat for Malaria in a High-Transmission Setting. [PDF]
Weynand A +13 more
europepmc +1 more source
Student Engagement in Program Evaluation: Redesigning the Premedical Curriculum Through Instructor-Learner Co-Creation. [PDF]
Sertsuwankul P +3 more
europepmc +1 more source

