Results 31 to 40 of about 2,446 (71)

Prevalence of high‐risk plasma p‐tau217 levels and 5‐year transition of risk status in 70‐year‐olds

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION High‐risk plasma p‐tau217 levels predict amyloid‐β pathology in Alzheimer's disease, but little is known about the prevalence and temporal dynamics in the general population. METHODS Participants from the Gothenburg H70 Birth Cohort Study in Sweden were examined (n = 1157) and re‐examined after 5–7 years (n = 771).
Anna Dittrich, Burak Arslan, Tobias Skillbäck, Lina Rydén, Hlin Kvartsberg, Johan Gobom, Kaj Blennow, Henrik Zetterberg, Silke Kern, Ingmar Skoog   +9 more
wiley   +1 more source

Utilização da Linguagem de Programação Scratch na Aprendizagem de Funções do 1º Grau

, 2020
Este trabalho investiga as possÃveis contribuições da linguagem de programação Scratch na introdução do conceito de funções, em uma turma de 9º ano de uma escola pública estadual de Santa Catarina, Brasil. A pesquisa ação foi realizada durante os meses de março até maio de 2019 e teve duração de 20 encontros, num total de 30 horas, com ...
Riboldi, Sandra Mara Oselame, Richert, Janice Teresinha   +1 more
openaire   +1 more source

Development and functional adaptation of intestinal macrophages across the lifespan

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
This article discusses intestinal macrophage development, including the influence of developmental origins and life stages; ontogeny and functional heterogeneity; preclinical and clinical evidence. Abstract Macrophages of the gastrointestinal system are central regulators of gut development, homeostasis and disease, yet their origin, functional ...
Baha Mustafa, Elisa L Hill‐Yardin, Sarah J Spencer   +2 more
wiley   +1 more source

SESCTV: por uma transgressão pela linguagem

Rumores, 2008
O SESCTV, canal de televisão administrado pelo SESC (Serviço Social do Comércio de São Paulo), caracteriza-se como uma iniciativa peculiar em seu âmbito midiático.
Taís Rios Salomão de Souza
doaj   +1 more source

Description of Austrocelis gen. nov. (Diptera: Periscelididae), including the description of eight new species and the diversity and abundance of the species in different strata of the Amazon Rainforest

Austral Entomology, Volume 65, Issue 2, May 2026.
Abstract Austrocelis gen. nov. is described based on the following characters: maxillary palpus short and spatulate; setae of the head elongate; face protrudent, with the dorsal portion flattened and oblique, and ventral portion shorter and recessed towards the mouth opening; wing banded, with setae present on dorsal surface of vein R1; surstylus ...
Rosaly Ale‐Rocha, Wayne N. Mathis
wiley   +1 more source

Gender responsiveness: Framing, programming, and the limits of transformative social protection in Ethiopia

International Social Security Review, Volume 79, Issue 2, Page 99-121, April/June 2026.
Gender responsiveness has emerged as a prominent concept in social protection policy, increasingly shaping donor agendas and national strategies. Yet despite widespread usage, we lack well‐defined analytical frameworks that allow for gender‐responsiveness assessments of entire national social protection systems.
Talea Grootenhuis
wiley   +1 more source

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities

European Journal of Neurology, Volume 33, Issue 3, March 2026.
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Alison Toomey, Jana Kleinerova, Ee Ling Tan, We Fong Siah, Peter Bede   +4 more
wiley   +1 more source

Frailty and Health Outcomes in People 65 Years or Older Living With Dementia: A Systematic Review of the Literature

Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.
ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda, Luis Carlos Venegas‐Sanabria, Marco Canevelli, Francesco Landi, Salomón Páez‐García, Kevin O'Hara‐Veintimilla, Lindsay Wallace, Kenneth Rockwood, Tommy Cederholm, Gustavo Duque, Mario Ulises Pérez‐Zepeda, Dag Aarsland   +11 more
wiley   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 354-366, February 2026.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The sortilin‐related receptor (SORL1) directs APP and Aβ trafficking within the retromer pathway. Cleavage at the cell surface releases soluble SORL1 (sSORL1) into cerebrospinal fluid (CSF). We examined whether CSF‐sSORL1 can serve as an in vivo marker of genetically impaired SORL1.
Matthijs W. J. de Waal, Sven J. van der Lee, Melanie Lunding, Lynn Boonkamp, Nolan Barrett, Giulia Monti, Anne Mette G. Jensen, Christian B. Vaegter, Jan Raska, Sona Cesnarikova, Jiri Sedmik, Calvin Trieu, Marjan M. Weiss, Rosalina van Spaendonk, Lisa Vermunt, Georgii Ozhegov, Niccolo Tesi, Marc Hulsman, Dovile Januliene, Arne Moller, Dasa Bohaciakova, Wiesje M. van der Flier, Olav M. Andersen, Charlotte E. Teunissen, Henne Holstege   +24 more
wiley   +1 more source