Results 21 to 30 of about 393 (135)

Aplicação da Programação Linear e do Problema do Transporte para otimização da produção agrícola

open access: yesCQD Revista Eletrônica Paulista de Matemática, 2020
Os recentes avanços tecnológicos nas atividades de produção agrícola tem em vista um conjunto de operações que buscam aumentar a produtividade, diminuir custos e otimizar processos de produção.
Glaucia Maria Bressan   +1 more
doaj  

Gender responsiveness: Framing, programming, and the limits of transformative social protection in Ethiopia

open access: yesInternational Social Security Review, Volume 79, Issue 2, Page 99-121, April/June 2026.
Gender responsiveness has emerged as a prominent concept in social protection policy, increasingly shaping donor agendas and national strategies. Yet despite widespread usage, we lack well‐defined analytical frameworks that allow for gender‐responsiveness assessments of entire national social protection systems.
Talea Grootenhuis
wiley   +1 more source

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Alison Toomey   +4 more
wiley   +1 more source

Problemas com o uso de programação linear com posterior arredondamento da solução ótima, em regulação florestal

open access: yesRevista Árvore, 2003
O principal objetivo deste trabalho foi avaliar, com a ajuda da Programação Inteira, as conseqüências do uso da Programação Linear com posterior arredondamento das respostas, com ênfase na regulação de florestas eqüiâneas.
Silva Gilson Fernandes da   +4 more
doaj  

Linear programming model to optimize the water resource use in irrigation projects: an application to the Senator Nilo Coelho Project Modelo de programação linear para otimizar o uso da água em projetos de irrigação: uma aplicação ao projeto Senador Nilo Coelho

open access: yesScientia Agricola, 1997
The main objective of this paper was to develop a separable linear programming model, considering a set of technical factors which may influence the profit of an irrigation project The model presents an objective function that maximizes the net income ...
J.A. Frizzone   +3 more
doaj   +1 more source

Frailty and Health Outcomes in People 65 Years or Older Living With Dementia: A Systematic Review of the Literature

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.
ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda   +11 more
wiley   +1 more source

Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The sortilin‐related receptor (SORL1) directs APP and Aβ trafficking within the retromer pathway. Cleavage at the cell surface releases soluble SORL1 (sSORL1) into cerebrospinal fluid (CSF). We examined whether CSF‐sSORL1 can serve as an in vivo marker of genetically impaired SORL1.
Matthijs W. J. de Waal   +24 more
wiley   +1 more source

Otimização de problemas de roteamento de veículos: soluções heurísticas

open access: yesCQD Revista Eletrônica Paulista de Matemática, 2020
Os custos com transporte e distribuição de produtos de um setor produtivo para seus locais de destino representam, geralmente, a maior parcela dos custos totais de produção.
Glaucia Maria Bressan   +1 more
doaj  

Algumas aplicações da análise limite numérica a problemas geotécnicos

open access: yesGeotecnia, 2004
Várias formulações numéricas da análise limite têm sido propostas para a solução de problemas geotécnicos de estabilidade. Nestas formulações, o problema de estabilidade é colocado como um problema da Programação Matemálica.
Eurípedes Vargas Jr.   +4 more
doaj   +1 more source

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

open access: yesGlia, Volume 74, Issue 1, January 2026.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli   +12 more
wiley   +1 more source

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