Results 81 to 90 of about 351 (209)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Quadern de dibuix de Joaquim Renart. 03, Realitzat entre el 25 de març de 1912 i el 30 de desembre de 1912

open access: yes, 1912
Quadern numerat al llom III. Imatges del Cafè Novetats de Barcelona, Montserrat, Hostalets de Balenyà, retrats de Josep Gudiol Ricart, de la família de Joaquim Renart i persones del seu entorn, etc.Inclou dibuixos i esbossos amb algunes anotacions ...
Renart, Joaquim, 1879-1961
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Quadern de dibuix de Joaquim Renart. 36, Realitzat entre el 19 de juliol i el 14 de desembre de 1924

open access: yes, 1924
Quadern numerat al llom XXXVI. Retrat de Joan Bru Balagué i imatges del Santuari de la Mare de Déu de Lord, del Monestir de Sant Pere de Galligants, de Berga, Tarragona, Hostalric, Navès, etc. Inclou dibuixos i esbossos amb algunes anotacions manuscrites
Renart, Joaquim, 1879-1961
core  

Sequencing and assembly of the Egyptian buffalo genome. [PDF]

open access: yesPLoS One, 2020
El-Khishin DA   +6 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Quadern de dibuix de Joaquim Renart. 11, Realitzat el 17 d'agost de 1917 i el 12 de febrer de 1918

open access: yes, 1917
Quadern numerat al llom XI. Imatges del castell, l'església i la festa major de Centelles, de l'escullera del Port de Barcelona, retrats de la família de Joaquim Renart i persones del seu entorn, etc.
Renart, Joaquim, 1879-1961
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Quadern de dibuix de Joaquim Renart. 07, Realitzat entre el 13 de maig de 1915 i el 24 de febrer de 1916

open access: yes, 1915
Quadern numerat al llom VII. Imatges de la font del Cerdà de Centelles, retrats de la família de Joaquim Renart i persones del seu entorn, etc. Inclou dibuixos i esbossos amb algunes anotacions manuscrites de l'artista i en alguns dels fulls fotografies ...
Renart, Joaquim, 1879-1961
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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