Results 1 to 10 of about 45,576 (293)

Dust-to-Gas and Refractory-to-Ice Mass Ratios of Comet 67P/Churyumov-Gerasimenko from Rosetta Observations

open access: yesSpace Science Reviews, 2020
This chapter reviews the estimates of the dust-to-gas and refractory-to-ice mass ratios derived from Rosetta measurements in the lost materials and the nucleus of 67P/Churyumov-Gerasimenko, respectively. First, the measurements by Rosetta instruments are
Mathieu Choukroun, K Altwegg, E Kuhrt
exaly   +2 more sources

Genome editing enables reverse genetics of multicellular development in the choanoflagellate Salpingoeca rosetta

open access: yeseLife, 2020
In a previous study, we established a forward genetic screen to identify genes required for multicellular development in the choanoflagellate, Salpingoeca rosetta (Levin et al., 2014).
David S Booth, Nicole King
doaj   +2 more sources

HighFold-MeD: a Rosetta distillation model to accelerate structure prediction of cyclic peptides with backbone N-methylation and d-amino acids [PDF]

open access: yesJournal of Cheminformatics
Abstract Cyclic peptides with backbone N-methylated amino acids (BNMeAAs) and D-amino acids (D-AAs) have gained increasing attention for their stability, membrane permeability, and other therapeutic potentials.
Zhigang Cao   +6 more
doaj   +2 more sources

Rosetta Neurons: Mining the Common Units in a Model Zoo [PDF]

open access: yesIEEE International Conference on Computer Vision, 2023
Do different neural networks, trained for various vision tasks, share some common representations? In this paper, we demonstrate the existence of common features we call "Rosetta Neurons" across a range of models with different architectures, different ...
Amil Dravid   +3 more
semanticscholar   +1 more source

Computational design of peptides to target NaV1.7 channel with high potency and selectivity for the treatment of pain

open access: yeseLife, 2022
The voltage-gated sodium NaV1.7 channel plays a key role as a mediator of action potential propagation in C-fiber nociceptors and is an established molecular target for pain therapy.
Phuong T Nguyen   +16 more
doaj   +1 more source

Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions

open access: yesFrontiers in Molecular Biosciences, 2022
Technologies for discovering peptides as potential therapeutics have rapidly advanced in recent years with significant interest from both academic and pharmaceutical labs.
Jeffrey K. Holden   +4 more
doaj   +1 more source

Effect of Potato Varieties on the Biology and Life Table Parameters of Potato Tuber Moth Phthorimaea operculella under Laboratory Conditions [PDF]

open access: yesJournal of Plant Protection and Pathology, 2021
Effects of different verities of potato tubers as a food Cara, Spunta and Rosetta on food ability, developing, fecundity and life table parameters of Phthorimaea operculellawere studiedunder laboratory conditions.Egg incubation period was longest in time
K. Draz   +4 more
doaj   +1 more source

Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles

open access: yesJournal of Chemical Information and Modeling, 2023
Thermostability enhancement is a fundamental aspect of protein engineering as a biocatalyst’s half-life is key for its industrial and biotechnological application, particularly at high temperatures and under harsh conditions. Thermostability changes upon
Francesca Peccati   +2 more
semanticscholar   +1 more source

Recent Advances in NMR Protein Structure Prediction with ROSETTA

open access: yesInternational Journal of Molecular Sciences, 2023
Nuclear magnetic resonance (NMR) spectroscopy is a powerful method for studying the structure and dynamics of proteins in their native state. For high-resolution NMR structure determination, the collection of a rich restraint dataset is necessary.
Julia Koehler Leman, Georg Künze
semanticscholar   +1 more source

A Rosetta Stone for Eccentric Gravitational Waveform Models [PDF]

open access: yesAstrophysical Journal, 2022
Orbital eccentricity is a key signature of dynamical binary black hole formation. The gravitational waves from a coalescing binary contain information about its orbital eccentricity, which may be measured if the binary retains sufficient eccentricity ...
A. Knee   +4 more
semanticscholar   +1 more source

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