Results 11 to 20 of about 45,576 (293)

Detection of Mycobacterium avium subsp. paratuberculosis from cattle and buffaloes in Egypt using traditional culture, serological and molecular based methods [PDF]

Veterinary World, 2014
Background: Johne's disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (MAP) represents a real threat to the agriculture and dairy food industries and believed to be a potential public health problem.
G. S. Abdellrazeq, M. M. El-Naggar, S. A. Khaliel , A. E. Gamal-Eldin   +3 more
doaj   +1 more source

Reliable protein-protein docking with AlphaFold, Rosetta, and replica-exchange

bioRxiv, 2023
Despite the recent breakthrough of AlphaFold (AF) in the field of protein sequence-to-structure prediction, modeling protein interfaces and predicting protein complex structures remains challenging, especially when there is a significant conformational ...
Ameya Harmalkar, Sergey Lyskov, Jeffrey J. Gray   +2 more
semanticscholar   +1 more source

MUPUS insertion device for the Rosetta mission

Journal of Telecommunications and Information Technology, 2023
An original mechanical device designed to insert a penetrator into a cometary nucleus in an almost gravityfree environment is described. The device comprises a hammer and a power supply system that stores electrical energy in a capacitor. The accumulated
J. Grygorczuk, M. Banaszkiewicz, K. Seweryn, T. Spohn   +3 more
semanticscholar   +1 more source

Macromolecular modeling and design in Rosetta: recent methods and frameworks

Nature Methods, 2020
The Rosetta software for macromolecular modeling, docking and design is extensively used in laboratories worldwide. During two decades of development by a community of laboratories at more than 60 institutions, Rosetta has been continuously refactored ...
Julia Koehler Leman, Brian D. Weitzner, Steven M. Lewis, Jared Adolf-Bryfogle, Nawsad Alam, Rebecca F. Alford, Melanie L. Aprahamian, D. Baker, Kyle A. Barlow, P. Barth, B. Basanta, B. Bender, Kristin M Blacklock, J. Bonet, S. Boyken, P. Bradley, C. Bystroff, Patrick Conway, Seth Cooper, B. Correia, B. Coventry, Rhiju Das, R. M. de Jong, F. DiMaio, Lorna Dsilva, Roland L. Dunbrack, Alex Ford, Brandon Frenz, Darwin Y. Fu, C. Geniesse, Lukasz Goldschmidt, R. Gowthaman, Jeffrey J. Gray, D. Gront, Sharon L. Guffy, S. Horowitz, Po-Ssu Huang, T. Huber, T. Jacobs, J. Jeliazkov, David K. Johnson, K. Kappel, J. Karanicolas, Hamed Khakzad, Karen R. Khar, S. Khare, Firas Khatib, A. Khramushin, I. King, Robert Kleffner, B. Koepnick, T. Kortemme, G. Kuenze, B. Kuhlman, Daisuke Kuroda, Jason W. Labonte, J. Lai, Gideon Lapidoth, Andrew Leaver-Fay, Steffen Lindert, Thomas W. Linsky, N. London, Joseph H. Lubin, Sergey Lyskov, Jack B. Maguire, L. Malmström, E. Marcos, Orly Marcu, Nicholas A. Marze, J. Meiler, Rocco Moretti, V. Mulligan, S. Nerli, Christoffer H Norn, Shane Ó’Conchúir, Noah Ollikainen, S. Ovchinnikov, M. Pacella, Xingjie Pan, Hahnbeom Park, Ryan E. Pavlovicz, Manasi A. Pethe, B. Pierce, K. B. Pilla, Barak Raveh, P. Renfrew, S. Burman, A. Rubenstein, Marion Sauer, A. Scheck, W. Schief, O. Schueler‐Furman, Yuval Sedan, A. M. Sevy, N. Sgourakis, Lei Shi, J. Siegel, Daniel‐Adriano Silva, Shannon T. Smith, Yifan Song, A. Stein, M. Szegedy, Frank D. Teets, Summer B. Thyme, R. Wang, A. Watkins, Lior Zimmerman, Richard Bonneau   +107 more
semanticscholar   +1 more source

Protein complex prediction using Rosetta, AlphaFold, and mass spectrometry covalent labeling

bioRxiv, 2022
Covalent labeling (CL) in combination with mass spectrometry can be used as an analytical tool to study and determine structural properties of protein-protein complexes.
Zachary C. Drake, Justin T. Seffernick, Steffen Lindert   +2 more
semanticscholar   +1 more source

The PyRosetta Toolkit: a graphical user interface for the Rosetta software suite. [PDF]

PLoS ONE, 2013
The Rosetta Molecular Modeling suite is a command-line-only collection of applications that enable high-resolution modeling and design of proteins and other molecules.
Jared Adolf-Bryfogle, Roland L Dunbrack
doaj   +1 more source

Intratumor heterogeneity: the Rosetta stone of therapy resistance

Cancer Cell, 2020
Advances in our understanding of molecular mechanisms of tumorigenesis have translated into knowledge-based therapies directed against specific oncogenic signaling targets.
A. Marusyk, M. Janiszewska, K. Polyak
semanticscholar   +1 more source

Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE). [PDF]

PLoS ONE, 2013
The Rosetta molecular modeling software package provides experimentally tested and rapidly evolving tools for the 3D structure prediction and high-resolution design of proteins, nucleic acids, and a growing number of non-natural polymers.
Sergey Lyskov, Fang-Chieh Chou, Shane Ó Conchúir, Bryan S Der, Kevin Drew, Daisuke Kuroda, Jianqing Xu, Brian D Weitzner, P Douglas Renfrew, Parin Sripakdeevong, Benjamin Borgo, James J Havranek, Brian Kuhlman, Tanja Kortemme, Richard Bonneau, Jeffrey J Gray, Rhiju Das   +16 more
doaj   +1 more source

Introduction to the Rosetta Special Collection. [PDF]

PLoS ONE, 2015
The Rosetta macromolecular modeling software is a versatile, rapidly developing set of tools that are now being routinely utilized to address state-of-the-art research challenges in academia and industrial research settings.
Sagar D Khare, Timothy A Whitehead
doaj   +1 more source

FARFAR2: Improved de novo Rosetta prediction of complex global RNA folds

Structure, 2020
Summary Predicting RNA 3D structures from sequence could accelerate understanding of the growing number of RNA molecules being discovered across biology. Rosetta’s Fragment Assembly of RNA with Full-Atom Refinement (FARFAR) has shown promise in community-
A. Watkins, R. Rangan, Rhiju Das
semanticscholar   +1 more source