Results 171 to 180 of about 190,895 (253)

Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials. [PDF]

Adv Sci (Weinh)
Kim EH, Kim M, Yoon H, Park K.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Bias-programmable linear-to-nonlinear photoresponse for filter-free single-pixel VIS-NIR discrimination. [PDF]

Nano Converg
Shin J, Alam M, Kim J, Lee YG, Jeon MK, Kim H, Jung GY.   +6 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Retraction for Lin and Lee, A dual self-regulatory platform for programmable biosynthesis of L-lysine-derived alkaloids. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

CMOS multifunctional programmable metachip for terahertz-integrated sensing and communication. [PDF]

Sci Adv
Shen Z, Guo K, Wu J, Fan K, Jing H, Deng H, Tian X, Jin B, You X, Zhao D.   +9 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Molecular velcro for precision genome repair. [PDF]

Nat Commun
Jerala R, Lainšček D.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Author Correction: Photonic neuromorphic accelerator for convolutional neural networks based on an integrated reconfigurable mesh

Communications Engineering
Aris Tsirigotis, George Sarantoglou, Stavros Deligiannidis, Erica Sánchez, David Sanchez, Ana Gutierrez, Adonis Bogris, Jose Capmany, Charis Mesaritakis   +8 more
doaj   +1 more source