Results 201 to 210 of about 5,689 (312)

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

open access: yesAdvanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao   +17 more
wiley   +1 more source

Aligned Nanostructures Resolve Zn2+ Transport Bottlenecks via Interfacial Kinetics–Diffusion Coupling in Aqueous Zinc‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
It is revealed that limited solid‐state Zn2⁺ diffusion within the cathode leads to interfacial Zn2⁺ accumulation, forming a transport bottleneck that distorts Zn2⁺ flux directionality. Through advanced analytical techniques, including in situ electrochemical impedance spectroscopy (EIS), distribution of relaxation time (DRT) analysis, and COMSOL ...
Juyeon Han   +4 more
wiley   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao   +18 more
wiley   +1 more source

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

open access: yesAdvanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun   +12 more
wiley   +1 more source

Enhancing grid connected wind energy conversion systems through fuzzy logic control optimization with PSO and GA techniques. [PDF]

open access: yesSci Rep
Borni A   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy