Results 51 to 60 of about 272,840 (340)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Research on transmission control method of tension tower hydraulic tension device based on PLC

Journal of Applied Science and Engineering, 2023
Using the traditional method to control the transmission process of the tension tower hydraulic tightening device, there is a problem of slow speed step response in the range of device operating speed from 12km/h to 32km/h.
Jinghui Zhang, Quanjun Yin, Haixing Yang, Zhongquan Jiao   +3 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Adaptive feedback analysis and control of programmable stimuli for assessment of cerebrovascular function [PDF]

, 2013
The assessment of cerebrovascular regulatory mechanisms often requires flexibly controlled and precisely timed changes in arterial blood pressure (ABP) and/or inspired CO2.
Allen, Robert, Birch, Anthony A, Bush, Glen, Fan, Lingke, Katsogridakis, Emmanuel, Panerai, Ronney B, Potter, John, Simpson, David M   +7 more
core   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Tissue Processor Based PLC (Programmable Logic Controller) [PDF]

, 2019
Tissue Processor Tissue Processor consists of consists of several stages of dehydration, clearing, and paraffin infiltration.Phase dehydration to remove water content in tissues by immersion into alcohol.
Ariswati, H. G. (Her), Indrato, T. B. (Tri), Neny, F. (Ferdianita)   +2 more
core  

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Intelligent Electro-Pneumatic Position Tracking System Using Improved Mode-Switching Sliding Control With Fuzzy Nonlinear Gain

IEEE Access, 2018
In this paper, a mode-switching sliding controller with the nonlinear gain generated by a fuzzy logic controller is put forward to enhance the tracking performance in an electro-pneumatic position control system which includes four solenoid ON-OFF valves
Zhonglin Lin, Tianhong Zhang, Qi Xie, Qingyan Wei   +3 more
doaj   +1 more source

SYSTEM SOFTWARE AT LABORATORY STAND „LIGHTS CONTROL ON THE BASIS OF PROGRAMMABLE LOGIC CONROLLER”

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022
The article is concerned with the issues of practical utilization of controllers for automation in various technical fields as example Mitsubishi controllers of MELSEC FX1N and FX3U series.
Laura Yesmakhanova, Raushan Dzhanuzakova, Bauyrzhan Myrkalykov   +2 more
doaj   +1 more source

Process Mining of Programmable Logic Controllers: Input/Output Event Logs

, 2019
This paper presents an approach to model an unknown Ladder Logic based Programmable Logic Controller (PLC) program consisting of Boolean logic and counters using Process Mining techniques.
Darabi, Houshang, Mokhtarian, Ilia, Theis, Julian   +2 more
core   +1 more source