Results 61 to 70 of about 364,910 (147)
Activin Signaling Inhibitors in Pulmonary Hypertension: A State‐of‐the‐Art Review
ABSTRACT Pulmonary arterial hypertension (PAH) is a disease of abnormal pulmonary vascular remodeling and vascular obliteration that results in right heart failure and death. PAH pathogenesis is strongly associated with mutations of the Transforming Growth Factor Beta (TGF‐β) superfamily signaling pathway, which has previously been challenging to ...
Sudarshan Rajagopal +10 more
wiley +1 more source
Non-linear finite element analyses of the aortic heart valve [PDF]
Includes bibliographical references.Finite element models of the aortic heart valve have been successfully used in the past to gain insight into the mechanics of the valve and to aid in understanding of valve failure.
Koch, Thorsten M
core +1 more source
Prognostic Value of Right Atrial Adverse Remodeling in Patients With Pulmonary Arterial Hypertension
ABSTRACT Assessment of right atrial (RA) structure helps monitor right heart (RH) function, critical for prognosis in pulmonary arterial hypertension (PAH). This study aims to assess the prognostic value of RA adverse remodeling (RAAR) with targeted therapy in PAH. Patients diagnosed with PAH between June 2013 and June 2024 were prospectively recruited.
Ji Zhao +13 more
wiley +1 more source
Development of Ultrasound Microbubbles and Phase Shift Microbubbles in Theranostics
Microbubbles have been originally designed for diagnostic applications. Over the years, microbubbles and phase shift microbubbles have been further developed for therapeutic indications. ABSTRACT Ultrasound is widely used for diagnostic imaging and therapy.
Emmanuelle J. Meuillet, Evan C. Unger
wiley +1 more source
ABSTRACT Background Atrial fibrillation is a primary cause of ischemic stroke, necessitating early detection, particularly in patients with embolic stroke of undetermined source. While nurseled continuous electrocardiogram monitoring allows real‐time rhythm assessment in acute stroke units, its specific clinical impact remains insufficiently clarified.
Junghee Han +3 more
wiley +1 more source
ABSTRACT Mucopolysaccharidosis type VI (MPS VI), a rare metabolic disorder, results from glycosaminoglycan accumulation in tissues, frequently leading to hyperplastic gingival alterations that necessitate comprehensive intervention. An 11‐year‐old male patient diagnosed with MPS VI required hospitalization due to complications associated with a ...
Regina Maria Raffaele +5 more
wiley +1 more source
Introduction Ventriculoperitoneal shunts are a common treatment of hydrocephalus in the first year of life; shunts can be fitted with pressure- regulated valves or flow-regulated valves.
Bilal Khaleel +8 more
doaj +1 more source
Branch retinal artery occlusion due to patent foramen ovale in a teenager
Abstract This report demonstrates the diagnostic evaluation and clinical management of a 16‐year‐old girl who developed branch retinal artery occlusion secondary to patent foramen ovale. The goal is to increase awareness of this rare presentation in adolescents among clinicians, with a summary of the important clinical features, multimodal imaging ...
Jie Zu +4 more
wiley +1 more source
This work presents a novel computational simulation framework for the study of pulmonary venous hemodynamics that integrates a closed‐loop lumped parameter model (LPM) of the cardiovascular system with a computational fluid dynamics (CFD) model of the pulmonary veins and left atrium. Coupling of the LPM and CFD models was accomplished through surrogate
Alessia Di Nardo +3 more
wiley +1 more source
Household magnets can change the programmable shunt valve in hydrocephalus patients
We found that external household magnets can change the pressure settings of programmable shunt valves. We compare two popular, adjustable, shunt valves used to regulate the cerebral-spinal fluid (CSF) of hydrocephalus patients: the Codman®Hakim ...
Liu, Sheng +3 more
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