Results 41 to 50 of about 907 (261)

Techniques de programmation d’un format télévisuel

Communication, 2014
The author examines a particular program format, the docusoap, and its place within the practices of television programming. She highlights the relationships between the networks’ practices of programming tv series and the content of their websites.
Céline Ferjoux
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

L’ANACHRONISME DE LA LÉGISLATION PUBLICITAIRE EN RÉPUBLIQUE DÉMOCRATIQUE DU CONGO [PDF]

Cahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2022
De nos jours, la publicité est omniprésente. Elle est devenue le trait caractéristique de la société de consommation et élément indispensable au fonctionnement de l’économie.
Dr Casimir ILUNGA KASAMBAY
doaj  

Hilbert's Programme [PDF]

Dialectica, 1958
Hilbert's plan for understanding the concept of infinity required the elimination of non-finitist machinery from proofs of finitist assertions. The failure of the original plan leads to a hierarchy of progressively less elementary, but still constructive methods instead of finitist ones (modified Hilbert programme). A mathematical proof of this failure
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimisation de la recharge d’un parc de batterie par l’approche informatique avec l’énergie solaire [PDF]

Revue de l'UKA
Cette recherche vise à améliorer la production de l’énergie verte produite par les panneaux solaires. Dans ce système, le stockage de ladite énergie est essentiel pour garantir un approvisionnement énergétique continu et équilibré, surtout pour des ...
Blaise MUBADI BAKAJIKA
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Dossier : Perspectives franco-brésiliennes autour de l’agroécologie – Aux frontières de l’agroécologie. Les politiques de recherche de deux instituts agronomiques publics français et brésilien★

Natures Sciences Sociétés, 2019
L’agroécologie en France et au Brésil résulte d’interactions entre la science, des pratiques agricoles et la politique. Nous analysons la manière dont deux institutions publiques de recherche agronomique, l’Empresa Brasileira de Pesquisa Agropecuária ...
Ollivier Guillaume, Bellon Stéphane, Deane de Abreu Sá Tatiana, Magda Danièle   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source