Results 241 to 250 of about 371,157 (314)

Reversal of Cushing syndrome by antibody-mediated neutralization of ACBP/DBI. [PDF]

open access: yesCell Stress
Shen Z   +5 more
europepmc   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

open access: yesAdvanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena   +11 more
wiley   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

open access: yesAdvanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi   +4 more
wiley   +1 more source

Ultrathin‐Gold‐Resonators‐Enabled Bolometers with High Linearity, Responsivity, and Repeatability

open access: yesAdvanced Science, EarlyView.
This work demonstrates ultrathin gold nanomechanical resonators operating in HF/VHF bands, unveiling their potential for laser power sensing. By exploiting frequency shifts resulting from laser‐induced thermal tension, these devices can function as sensitive nanoscale bolometers, with outstanding linearity, responsivity, and repeatability. The findings
Jiaqi Wu   +9 more
wiley   +1 more source

Accretion of volatile elements on Earth without the need of a late veneer. [PDF]

open access: yesSci Adv
Calvo L   +8 more
europepmc   +1 more source

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