Results 241 to 250 of about 371,126 (314)

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Gut Microbiota Composition and Sleep in Preschoolers: The ELFE Birth Cohort Study. [PDF]

Children (Basel)
Houshialsadat Z, Zaros C, Butel MJ, Charles MA, Toubon G, Plancoulaine S.   +5 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Decline in prevalence and intensity of onchocerciasis in sentinel villages along the Comoé river in Cascades region, Burkina Faso following five years of community directed bi-annual ivermectin treatment, 2011-2015. [PDF]

BMC Infect Dis
Nikièma AS, Koala L, Unnasch TR, Diendéré J, Ouédraogo MW, Compaoré J, Kafando CM, Bougouma C, Faye B, Traoré S, Dabiré RK.   +10 more
europepmc   +1 more source

Programme de recherche blanc de l'ANR

Le Cresson veille et recherche…, 2010
openaire   +1 more source

Ultra‐High Friction and Adhesion in Hydrogel Layer Driven by Wet‐to‐Dry Transition Dynamics

Advanced Science, EarlyView.
This work reveals a critical wet‐to‐dry transition in polyacrylamide hydrogel layers that induces volumetric shrinkage, resulting in enhanced interfacial contact and dramatically increased friction and adhesion. Leveraging this transition enables strong, reversible gripping on diverse surfaces, offering new insights for hydrogel‐based gripping ...
Chenxu Liu, Tianhui Sun, Wenqing Chen, Hongjian Zhang, Pan Huang, Lin Yang, Yuan Yao, Qiongyao Peng, Ying Hu, Yonggang Meng, Yu Tian, Hongbo Zeng   +11 more
wiley   +1 more source

Is PARTNER, a hybrid HABIT-ILE programme with parent coaching, as effective as standard HABIT-ILE in children with cerebral palsy aged 3-5? A protocol for a multicentre, randomised controlled trial. [PDF]

BMJ Open
Demas J, Jacquemot D, Bouvier S, Goff ML, Carcreff L, Dinomais M, Vuillerot C, Brochard S, Dubois A, Bailly R.   +9 more
europepmc   +1 more source

Vers un programme de recherche

, 2017
Magri, Susanna, Tissot, Sylvie
openaire   +2 more sources

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Soins de santé primaires pour les personnes ayant reçu une transplantation rénale. [PDF]

CMAJ
Rampersad C, Bau J.
europepmc   +1 more source