Results 161 to 170 of about 487,302 (334)

Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro [PDF]

, 2009
Shashini C Arambage, Karen M. Grant, Ian Pardo, Lisa Ranford‐Cartwright, Hilary Hurd   +4 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Prognostic risk modeling of endometrial cancer using programmed cell death-related genes: a comprehensive machine learning approach [PDF]

Tianshu Chen, Yuhan Yang, Zhizhong Huang, Feng Pan, Zaiyu Xiao, K. Gong, Wenguang Huang, Xu Liu, Xueqin Liu, Caiyun Fang   +9 more
openalex   +1 more source

The PET1-CMS Mitochondrial Mutation in Sunflower Is Associated with Premature Programmed Cell Death and Cytochrome c Release [PDF]

, 2001
Janneke Balk, Christopher J. Leaver
openalex   +1 more source

Investigating Mechanisms of Response or Resistance to Immune Checkpoint Inhibitors by Analyzing Cell-Cell Communications in Tumors Before and After Programmed Cell Death-1 (PD-1) Targeted Therapy: An Integrative Analysis Using Single-cell RNA and Bulk-RNA Sequencing Data [PDF]

, 2021
Yiquan Jiang, Zixian Wang, Ming Zhong, Lujun Shen, Xue Han, Xuxiazi Zou, Xin-Yi Liu, Yinan Deng, Yang Yang, Guihua Chen, Wuguo Deng, Jinhua Huang   +11 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Clinical, Endoscopic and Histologic Features of Lung Cancer Patients with Programmed Cell Death Protein 1 (PD-1) Inhibitor-associated Diarrhea and Colitis

, 2018
Noriko Mitome, Haruhiro Saito, Yuji Shibata, Isuke Shimokawaji, Tetsuro Kondo, Terufumi Kato, Tomoyuki Yokose, Kouzo Yamada   +7 more
openalex   +2 more sources

Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1 [PDF]

, 2019
Yujie Zhu, Xiao Hu, Lin Feng, Zhenrong Yang, Lulin Zhou, Xinchun Duan, Shujun Cheng, Wen Zhang, Binlei Liu, Kaitai Zhang   +9 more
openalex   +1 more source

Programmed cell death 1 inhibitors with or without concurrent brain radiotherapy for lung cancer patients with brain metastases [PDF]

, 2021
Yu Huang, Huanhuan Li, Ling Peng, Fan Tong, Lu Wen, Ruiguang Zhang, Shishi Cheng, Xiaorong Dong   +7 more
openalex   +1 more source