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Programmed Cell Death

Science, 1996
Letters from: [ Jan Novak ][1] [ Alice B. Fulton ][1] [ Jean Claude Ameisen ][1] Jean Claude Ameisen's Perspective “The origin of programmed cell death [PCD]” ([31 May, p. 1278][2]) discusses possible evolutionary roots of cell suicide.
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The biochemistry of programmed cell death

The FASEB Journal, 1995
Programmed cell death (PCD) is involved in the removal of superfluous and damaged cells in most organ systems. The induction phase of PCD or apoptosis is characterized by an extreme heterogeneity of potential PCD-triggering signal transduction pathways.
Kroemer, Guido   +4 more
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Chlamydia and programmed cell death

Current Opinion in Microbiology, 2006
Discordant views regarding host cell death induction by Chlamydia are likely owing to the different methods used for evaluation of apoptosis. Apoptotic and non-apoptotic death owing to both caspase-dependent and -independent activation of the Bax protein occur late in the productive growth cycle. Evidence also suggests that Chlamydia inhibits apoptosis
Isao Miyairi, Gerald I. Byrne
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Programmed cell death and cancer [PDF]

open access: possiblePostgraduate Medical Journal, 2009
Abstract Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells.
Peng Zl, Sun Y
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Programmed cell death and radioresistance

Cancer and Metastasis Review, 1996
Whereas apoptosis is a critical mode of cell deletion in normal organism development, apoptotic cells are also observed in tumors, especially following cytotoxic treatments, leading to questions about their role in tumor response to therapy. We have conducted a series of studies using murine tumor models and found that the ability of the tumor cells to
L. C. Stephens   +2 more
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Programmed cell death in invertebrates

Current Opinion in Genetics & Development, 1996
Genetic studies of programmed cell death in Caenorhabditis elegans and Drosophila melanogaster have led to the identification of several invertebrate cell death genes. In C. elegans, ced-3 and ced-4 function to kill cells, whereas ced-9 protects cells from death.
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Programmed Cell Death in Prokaryotes [PDF]

open access: possibleCritical Reviews in Microbiology, 1997
Programmed cell death (PCD), also referred to as apoptosis, is a cellular "suicide" mechanism, based on information from its own internal metabolism, environment, developmental history, and genome. This system was described in eukaryotes continuously along evolution, through amoebae, nematodes, insects, and animals.
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Programmed Cell Death

1997
How Hormones Regulate Programmed Cell Death During Amphibian Metamorphosis J.R. Tata. Activation of Matrix Metalloproteinase Genes during Thyroid Hormne-Induced Apoptotic Tissue Remodeling Y.-B. Shi, A. Ishizuya-Oka. Mechanisms by Which Matric Metalloproteinases May Influence Apoptosis W.C. Powell, L.M. Matrisian.
David W. Scott   +3 more
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Programmed Cell Death in Development

1995
Although cell death has long been recognized to be a significant element in the process of embryonic morphogenesis, its relationships to differentiation and its mechanisms are only now becoming apparent. This new appreciation has come about not only through advances in the understanding of cell death in parallel immunological and pathological ...
Michael A. Wride, Esmond J. Sanders
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Programmed cell death in Hydra

Seminars in Cancer Biology, 2007
Hydra is one of the simplest metazoans and thus an important model organism for studies on the evolution of developmental mechanisms in multi-cellular animals. In Hydra apoptosis is involved in the regulation of cell numbers in response to feeding, in regeneration and in the removal of non-self cells. It also participates in the maintenance of cellular
Olga Alexandrova, Angelika Böttger
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