Results 171 to 180 of about 10,065,028 (360)

Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring

, 2013
Maik Dahlhoff, Stefan M. Pfister, Andreas Blutke, Jan Rozman, Martin Klingenspor, Manuel J. Deutsch, Birgit Rathkolb, Barbara Fink, Martina Gimpfl, Martin Hrabě de Angelis, A. Roscher, Eckhard Wolf, Regina Ensenauer   +12 more
openalex   +2 more sources

A cluster-genetic programming approach for detecting pulmonary tuberculosis

, 2021
Adane Nega Tarekegn, Tamir Anteneh Alemu, Alemu Kumlachew Tegegne   +2 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Enhancing SNV identification in whole-genome sequencing data through the incorporation of known genetic variants into the minimap2 index

BMC Bioinformatics
Motivation Alignment of reads to a reference genome sequence is one of the key steps in the analysis of human whole-genome sequencing data obtained through Next-generation sequencing (NGS) technologies. The quality of the subsequent steps of the analysis,
Egor Guguchkin, Artem Kasianov, Maksim Belenikin, Gaukhar Zobkova, Ekaterina Kosova, Vsevolod Makeev, Evgeny Karpulevich   +6 more
doaj   +1 more source

The Impact of Implementing a Pharmacist-led Deprescribing Program on Medication Adherence among Hemodialysis Patients

, 2023
M. Falah, Ali Lateef Jasim
openalex   +2 more sources

Program [PDF]

American Journal of Human Biology, 1990
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Theory of linear and integer programming

Wiley-Interscience series in discrete mathematics and optimization, 1986
A. Schrijver
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Improved approximation algorithms for maximum cut and satisfiability problems using semidefinite programming

JACM, 1995
M. Goemans, David P. Williamson
semanticscholar   +1 more source