We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The maternal-infant microbiome axis as an epigenetic and immunometabolic orchestrator: redefining early-life programming and precision interventions for lifelong women's and children's health. [PDF]
Mukherjee A.
europepmc +1 more source
New Algorithm for the Diagnosis of HypertensionCanadian Hypertension Education Program Recommendations (2005) [PDF]
Martin G. Myers +5 more
openalex +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Enhancing Computational Thinking and Programming Logic Skills with App Inventor 2 and Robotics: Effects on Learning Outcomes, Motivation, and Cognitive Load. [PDF]
Huang YT, Li CL, Chang CC, Tarng W.
europepmc +1 more source
COMMUNITY-WIDE REDUCTION IN PREVALENCE AND INTENSITY OF INTESTINAL HELMINTHS AS A COLLATERAL BENEFIT OF LYMPHATIC FILARIASIS ELIMINATION PROGRAMS [PDF]
Madsen Beau de Rochars +9 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Fabricating liquid crystal actuators: from small pre-strain to large actuation strain. [PDF]
He E +10 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Early Impact of a Co-Designed Playgroup for Children With Medical Complexity: A Mixed Methods Pilot Study. [PDF]
Nizzer S, McKay SM, Wong M, Nichol K.
europepmc +1 more source

