Results 71 to 80 of about 323,453 (199)

Building a Rural, Coalition-Based Approach to Youth Substance Use Prevention: The Drug Free Dickson Coalition Model. [PDF]

J Public Health Manag Pract
Thompson KR.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reflective AI use and student engagement in AI-supported programming: technology acceptance, programming self-efficacy, and behavioral trace evidence. [PDF]

Front Psychol
Wang S, Zhao J.
europepmc   +1 more source

PROGRAM [PDF]

Neurotherapeutics, 2016
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Dual-Programmable 2M NOR Flash Architecture for Energy-Efficient In-Memory Computing. [PDF]

Adv Sci (Weinh)
Kim S, Ryu D, Kim H, Jung S, Kim MH.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Real-world deep brain stimulation programming practices for Parkinson's disease in India: variability, technology adoption, and emerging trends from a multicentre clinician survey across India. [PDF]

Front Neurol
Pal PK, Rajan R, Krishnan Nair S, Yadav R, Anand M, Balakrishnan S, Baldia M, Banarjee AD, Borgohain R, Ganguly J, Ginjupally DR, Holla VV, Hosurkar G, Kamble N, Kandadai RM, Kayal A, Kohat AK, Kumar H, Mahale RR, Matur V, Prasad S, Shiva Kumar R, Sheikh A, Shetty K, Singh S, Venkatachalam A, Shankar V, Vysakh KV, Yareeda S.   +28 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Image-guided programming improves motor control in chronic subthalamic nucleus deep brain stimulation in Parkinson's disease: A prospective study. [PDF]

J Parkinsons Dis
Lee JS, Ha J, Kim S, Cho JW, Lee JI, Youn J.   +5 more
europepmc   +1 more source