Results 151 to 160 of about 682,366 (313)

Development Scaffolding for Construction of Evaluation Instrument Training Program on The Cognitive Domain For Senior High School Physics Teachers and The Same Level [PDF]

, 2017
Wahyuni Arif, Andi Suhandi, Ida Kaniawati, Ahmad Budi Setiawan   +3 more
openalex   +1 more source

PClean: Bayesian Data Cleaning at Scale with Domain-Specific Probabilistic Programming [PDF]

, 2020
Alexander K. Lew, Monica Agrawal, David Sontag, Vikash K. Mansinghka   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A Domain-Theoretic Model Of Nominally-Typed Object-Oriented Programming

, 2014
Moez A. AbdelGawad
openalex   +1 more source

Cognitive Diagnosis for Programming Domains

, 2023
Yongfeng Huang, Kaiyuan Wang
openaire   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Programmed Search in a Timetabling Problem over Finite Domains

, 2007
Ramón González-del-Campo, Fernando Sáenz-Pérez   +1 more
openalex   +1 more source

Comparing Planning Domain Models Using Answer Set Programming

, 2023
Lukáš Chrpa, Carmine Dodaro, Marco Maratea, Marco Mochi, Mauro Vallati   +4 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source