Results 51 to 60 of about 273,438 (282)
, 2018 The extremum value theorem for function spaces plays the central role in optimal control. It is known that computation of optimal control actions and policies is often prone to numerical errors which may be related to computability issues.
Osinenko, Pavel, Streif, Stefan
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Child friendly spaces impact across five humanitarian settings: a meta-analysis
BMC Public Health, 2019 Background Humanitarian crises present major threats to the wellbeing of children. These threats include risks of violence, abduction and abuse, emotional distress and the disruption of development.
Sabrina Hermosilla +4 more
doaj +1 more source
Programming Abstractions for Data Sharing in Distributed Spaces
, 2017 The cost of moving data is becoming a dominant factor for performance and energy efficiency in high-performance computing systems. To minimize data movement, applications have to consider data placement in order to optimize data transfer between processing units.
openaire +1 more source
Threads and Or-Parallelism Unified
, 2010 One of the main advantages of Logic Programming (LP) is that it provides an excellent framework for the parallel execution of programs. In this work we investigate novel techniques to efficiently exploit parallelism from real-world applications in low ...
Carro +12 more
core +1 more source
, 1994 : Metric spaces are inevitably Hausdorff and so cannot, for example, be used to study non‐Hausdorff topologies such as those required in the Tarskian approach to programming language semantics.
S. Matthews
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Generic Programming in Space and Time: Abstractions for High Performance Code Generation
, 2017 The development of high performance libraries on modern hardware is extremely difficult and often requires reimplementation or retuning with every new processor generation. Program generators that produce such libraries automatically from a high level description are an appealing solution but only few exist to date. The difficulty is in both the design
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source