Results 91 to 100 of about 1,534,832 (298)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

PROGRAMMING IN NATURAL LANGUAGE: PUBLICATIONS REVIEW

open access: yesInformatika, 2016
Paper addresses a number of scientific papers devoted to the issues of programming languages close to natural languages. Description of classical approaches to the design of natural programming languages and new approaches that have made the development ...
E. G. Luttsev
doaj  

On the Evolution of Programming Languages

open access: yesCoRR, 2020
This paper attempts to connects the evolution of computer languages with the evolution of life, where the later has been dictated by \emph{theory of evolution of species}, and tries to give supportive evidence that the new languages are more robust than the previous, carry-over the mixed features of older languages, such that strong features gets added
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Design considerations of an intelligent tutoring system for programming languages [PDF]

open access: yes
The overall goal of the thesis is to attempt to highlight the major topics which must be considered in the design of any Intelligent Tutoring System and to illustrate their application within the particular domain of LISP programming.
Elsom-Cook, Mark
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Wybe: Design of a Programming Language

open access: yesSoftware
We propose a set of design principles to guide the design of a programming language intended for general, practical use. These principles center around supporting the development of robust programs, supporting independent development, the evolution of ...
Peter Schachte
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Mediated Transfer in Teaching Programming Using Visual Programming Languages [PDF]

open access: yesPolitehnika, 2018
Novice programmers find learning programming difficult and challenging. That perception has a negative effect on motivation, and problems which students face during their first learning attempts only confirm their expectations so they give up.
Divna Krpan, Damir Brčić
doaj  

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