Results 151 to 160 of about 4,039,197 (315)

Assessing family planning progress in exemplar countries: development of a conceptual framework and case study methodology. [PDF]

BMJ Glob Health
Memon ZA, Najmi H, Mian A, St-Onge Ahmad S, Islam M, Samuel K, Temmerman M, Mir AM, Sathar Z, Bhutta ZA.   +9 more
europepmc   +1 more source

Vascular endothelial growth factor: basic science and clinical progress.

Endocrine reviews, 2004
N. Ferrara
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Policy in practice: assessing Senegal's family planning progress using a mixed-methods approach. [PDF]

BMJ Glob Health
Faye SLB, Sow GHC, Faye RA, Ndong MG, Tine ME, Diagne NA, Doucoure A, Najmi H, Zulfiqar M, St-Onge Ahmad S, Memon ZA, Bhutta Z.   +11 more
europepmc   +1 more source

The clinical progress of mRNA vaccines and immunotherapies

Nature Biotechnology, 2022
A. Barbier, A. Jiang, P. Zhang, R. Wooster, Daniel G. Anderson   +4 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

SDG progress and the challenge of inclusive wealth sustainability. [PDF]

iScience
Sugiawan Y, Managi S.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Getting Back on the Path to Eliminating HIV in Children. [PDF]

J Int AIDS Soc
Siberry GK.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source