Results 131 to 140 of about 2,867,307 (315)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Five semi-finalists for the Miss Century of Progress beauty contest
, 1933 "Five Polish girls selected to appear in the semi-finals of the Miss Century of Progress beauty contest Saturday night: Helen Zadora, 11440 Stephenson, Loretta Gondek, 2135 Webster, Sylvia Lopacinski, 4457 South Sawyer, Irene Napientek, 3350 ...
Kaufmann & Fabry Co.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Exterior view of the Italian Pavilion at the Century of Progress International Exposition.
, 1933 The Pavilion's giant airplane-shaped design celebrated Italo Balbo's transatlantic flight to the Century of Progress in 1933. Balbo was an Italian fascist, a leader of the Blackshirts, and a minister in Benito Mussolini's government.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Scientific ReportsPhenotypic degeneration in Cordyceps militaris poses a significant concern for producers, yet the mechanisms underlying this phenomenon remain elusive.
Chinh Q. Hoang +5 more
doaj +1 more source
Progress in phototransduction [PDF]
Biophysics of Structure and Mechanism, 1983 STAVENGA, DG, DEGRIP, WJ, Grip, W.J. de
openaire +3 more sources
Work in Progress Issue no.60 - Negotiations, another site of struggle
, 1989 The air is thick with talk about negotiating South Africa's future. From the government of FW de Klerk and PW Botha to the rulers of England, the Soviet Union, the United States of America and West Germany; from the National and Democratic Parties to the
Work in progress (WIP)
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