Results 121 to 130 of about 3,448,762 (309)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Work in Progress Issue no.59 - Roads to congress
South Africa is moving into its fourth year of continuous emergency rule. And with the exception of a few months during 1986, some areas are entering their fifth year under these conditions. The effects of permanent emergency rule have been traumatic and
Work in progress (WIP)
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Five semi-finalists for the Miss Century of Progress beauty contest
"Five Polish girls selected to appear in the semi-finals of the Miss Century of Progress beauty contest Saturday night: Helen Zadora, 11440 Stephenson, Loretta Gondek, 2135 Webster, Sylvia Lopacinski, 4457 South Sawyer, Irene Napientek, 3350 ...
Kaufmann & Fabry Co.
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Exterior view of the Italian Pavilion at the Century of Progress International Exposition.
The Pavilion's giant airplane-shaped design celebrated Italo Balbo's transatlantic flight to the Century of Progress in 1933. Balbo was an Italian fascist, a leader of the Blackshirts, and a minister in Benito Mussolini's government.
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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Newsletter published from Galveston Progress Committee in Galveston, Texas describing progress and effectiveness of various city planning and publicity programs.
Galveston Progress Committee
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This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

