Results 111 to 120 of about 2,867,307 (315)

Parole authorities meet at A Century of Progress

open access: yes, 1933
Parole authorities meet at A Century of Progress. William E. Padden, of Chicago, executive secretary of the Central States Parole conference, is shown (left) welcoming Ed H.
Kaufmann & Fabry Co.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

In ​Progress

open access: yes
The Zero-Weighted Eta function is defined by \[ \tilde{\eta}(s) = \sum_{k=1}^{\infty} \frac{(-1)^{k-1}}{k^s s^k}. \] Its Mellin-regularized representation \[ \tilde{\eta}_A(s) = \frac{1}{\Gamma(s)} \int_0^\infty \frac{x^{s-1}}{1 + A e^x} \, dx, \quad A \in (0,1), \] satisfies the Zero-Weighted Functional Equation (ZWF): \[ \frac{\tilde{\eta}_B(1-s ...
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Henry Sheldon christens 'A Century of Progress Ranger'

open access: yes, 1933
"Henry Sheldon, Chicago policeman, breaks a bottle a bottle of sparkling Burgundy over 'A Century of Progress Ranger' officially launching a Hudson Terraplane Coach on a ruggedness run, which will cover four states.
Kaufmann & Fabry Co.
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Mobility and urban form effects on air quality in New York City

open access: yesInternational Journal of Sustainable Energy
This study presents an integrated framework for assessing the interdependent impacts of urban mobility, land use, walkability, and air pollution on environmental outcomes in New York City. It offers a holistic approach to understanding how urban form and
Swati Sharma   +7 more
doaj   +1 more source

Work in Progress Issue no.59 - Roads to congress

open access: yes, 1989
South Africa is moving into its fourth year of continuous emergency rule. And with the exception of a few months during 1986, some areas are entering their fifth year under these conditions. The effects of permanent emergency rule have been traumatic and
Work in progress (WIP)
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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