Results 111 to 120 of about 3,448,762 (309)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Henry Sheldon christens 'A Century of Progress Ranger'
"Henry Sheldon, Chicago policeman, breaks a bottle a bottle of sparkling Burgundy over 'A Century of Progress Ranger' officially launching a Hudson Terraplane Coach on a ruggedness run, which will cover four states.
Kaufmann & Fabry Co.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Parole authorities meet at A Century of Progress
Parole authorities meet at A Century of Progress. William E. Padden, of Chicago, executive secretary of the Central States Parole conference, is shown (left) welcoming Ed H.
Kaufmann & Fabry Co.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Work in Progress Issue no.4 - The Swaziland connection
This is the 4th issue of Work in Progress, and the editors would like to bring a few matters to the attention of readers and contributors. Language: We have received a number of critical comments, suggesting that some of the language used in WIP articles
Work in progress (WIP)
core
Mobility and urban form effects on air quality in New York City
This study presents an integrated framework for assessing the interdependent impacts of urban mobility, land use, walkability, and air pollution on environmental outcomes in New York City. It offers a holistic approach to understanding how urban form and
Swati Sharma +7 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Long-term static strength is one of the most important parameters to be calculated at the life-time design stage of aircraft engine turbine blades. The importance of studying and modeling this parameter is based on many factors.
Yevhen Nemanezhyn +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

