Results 191 to 200 of about 69,815 (251)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

[Recent progress in platelet laboratory testing].

open access: yes[Rinsho ketsueki] The Japanese journal of clinical hematology, 2014
openaire   +2 more sources

Progress testing internationally

Medical Teacher, 2010
In front of you is a themed issue on progress testing. Progress testing is a form of assessment where groups of learners of different seniority (i.e., different classes in a curriculum) are given t...
Freeman, Adrian   +3 more
openaire   +2 more sources

Research Progress of Flaky Tests

2021 IEEE International Conference on Software Analysis, Evolution and Reengineering (SANER), 2021
A flaky test is a test that both passes and fails periodically without any code changes, and its uncontrolled uncertainty will destroy the value of the test suites and even cause developers to distrust the test results. Recently, researches in the flaky test have received broad attention in the software test community to reduce the manual maintenance ...
Wei Zheng 0006   +4 more
openaire   +1 more source

Assessment of progress tests

Medical Education, 2005
Background  Progress testing is a form of longitudinal examination which, in principle, samples at regular intervals from the complete domain of knowledge considered a requirement for medical students on completion of the undergraduate programme.
McHarg, J   +5 more
openaire   +3 more sources

Testing the Progressive Nature of Alcoholism

International Journal of the Addictions, 1992
The authors employed a new data collection methodology to assess Jellinek's progressive model of alcoholism. Data were collected to explore whether (a) symptoms occurred in four distinct phases, one phase following another, as described by Jellinek's model; (b) the phase markers and the phases of the symptom progression follow one another as predicted ...
R D, Yeager, N J, Piazza, J W, Yates
openaire   +2 more sources

Cumulative achievement testing: Progress testing in reverse

Medical Teacher, 2010
This collaborative project between the National Board of Medical Examiners (NBME) and Case Western Reserve University (CWRU) School of Medicine explored the design and use of cumulative achievement tests in basic science education. In cumulative achievement testing, integrative end-of-unit tests are deliberately constructed to systematically retest ...
D B, Swanson, K Z, Holtzman, A, Butler
openaire   +2 more sources

Antibody tests: progress and pitfalls

Clinical and Diagnostic Virology, 1996
Serological tests are the basis for most laboratory virological diagnosis. The recent development of DNA amplification methods, allowing the detection of viral nucleotide sequences in clinical specimens, raises the question of whether or not these will supersede antibody tests.To assess the current strengths and weaknesses of current viral serology in ...
openaire   +2 more sources

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