Results 191 to 200 of about 1,261,208 (309)

Real-World Progression-Free Survival and Healthcare Resource Utilization Associated with Daratumumab Use in Transplant-Ineligible Multiple Myeloma Patients in Italy. [PDF]

Clinicoecon Outcomes Res
Perrone V, Barilà G, Franceschini L, Mele G, Mazzoni S, Cappuccilli M, Andretta M, Bacca M, Bartolini F, Barbieri A, Blasi A, Chinellato A, Dell'Orco S, Ferrante F, Lombardi R, Mancini D, Pagliaro R, Paciello A, Pastorello M, Procacci C, Ricciardulli D, Ubertazzo L, Valpondi P, Zucchi A, Degli Esposti L.   +24 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Prognostic impact of sarcopenia on 5-year overall and progression-free survival in lung cancer patients: a prospective cohort study. [PDF]

Front Nutr
Zhao T, Li XQ, Shi Z, Zhang CB, Zhu YG.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Impact of Achieving Progression-Free Survival 24 on Subsequent Overall Survival in Diffuse Large B-Cell Lymphoma Patients. [PDF]

Cancer Sci
Fujimoto A, Munakata W, Ogawa G, Machida R, Suzuki T, Shimada K, Kobayashi T, Ohmachi K, Kinoshita T, Ando K, Maruyama D, Nagai H.   +11 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Real-world comparison of progression-free survival and time to next therapy in 761 patients with newly diagnosed multiple myeloma. [PDF]

Blood Adv
Mian H, Arribas M, Fonseca R, Mutterback E, Shahid O, Gouda R, Pond GR, Visram A.   +7 more
europepmc   +1 more source

Progression-free or overall survival…revisited in BOLERO-2 [PDF]

Indian Journal of Medical and Paediatric Oncology, 2014
openaire   +3 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

An 18F-FDG PET/CT-based radiomics nomogram for predicting progression-free survival in nasopharyngeal carcinoma: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Lin J, Liu J, Liu Y, Cao Z, Wen D, Wu Y, Wang Z, Zhang X, Wang B, Li S, Dong X.   +10 more
europepmc   +1 more source