Results 21 to 30 of about 5,027,565 (330)
Somatic mutations of the estrogen receptor 1 gene (ESR1) is an emerging mechanism of acquired resistance to endocrine therapy in hormonal breast cancers.
David Barua +3 more
doaj +1 more source
The miR-17-92 cluster: Yin and Yang in human cancers
MicroRNAs (miRNAs) are non-coding RNAs which modulate gene expression via multiple post-transcriptional mechanisms. They are involved in a variety of biological processes, including cell proliferation, metastasis, metabolism, tumorigenesis, and apoptosis.
Wenyuan Zhao +3 more
doaj +1 more source
IntroductionThis study explores the relationship between perceived school climate and exercise behavior among obese adolescents, as well as the multiple mediating effects of perseverance qualities and exercise benefits.MethodsA survey was conducted on ...
Yao Yin +4 more
doaj +1 more source
Progress in Progression? [PDF]
Diabetic nephropathy is the major cause of ESRD in the United States.1 Unfortunately, only angiotensin-converting enzyme inhibitors or angiotensin type 1 receptor blockers are registered for slowing the progression of diabetic nephropathy—but they do not halt progression.2–5 Given that diabetic nephropathy costs the health care system close to $30 ...
openaire +1 more source
Intraocular Pressure Fluctuation: Is It Important? [PDF]
Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of glaucoma. Previous prospective, randomized, long-term studies have demonstrated the strength of IOP reduction in slowing the progression of disease.
Caprioli, Joseph, Kim, Ji Hyun
core +2 more sources
Teaching progressions and learning progressions [PDF]
AbstractJust as students undergo “learning progressions” in moving from naivety to mastery of biochemical topics, faculty experience “teaching progressions” as they experiment with pedagogy, listen to students' feedback, and become members of a community of educators. An important element of both teaching and learning is assessment.
openaire +2 more sources
IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source
The immune system is a fundamental part of the tumor microenvironment. In particular, cytotoxic lymphocytes, such as cytolytic T cells and natural killer cells, control tumor growth and disease progression by interacting and eliminating tumor cells.
Hannah Wurzer +3 more
doaj +1 more source
Front progression for the East model [PDF]
The East model is a one-dimensional, non-attractive interacting particle system with Glauber dynamics, in which a flip is prohibited at a site $x$ if the right neighbour $x+1$ is occupied.
Blondel, Oriane
core +1 more source
Progressive Thoughts about Progressive Disease [PDF]
In this issue of Clinical Cancer Research , Desai et al. ([1][1]) present evidence that new modules appearing in preexisting lesions can represent clonally resistant populations. Imatinib mesylate, the prototypic oral tyrosine kinase inhibitor that has activity against ABL, KIT, and platelet-
openaire +2 more sources

