Results 11 to 20 of about 1,133,949 (262)
BMC Cancer, 2023 Background Endocrine-resistant breast cancers have elevated expression of XBP1, where it drives endocrine resistance by controlling the expression of its target genes.
David Barua +5 more
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Progression-free survival according to MTV.
, 2022 Progression-free survival according to MTV.
Nina Jehanno (11949663) +8 more
core +1 more source
Frontiers in Immunology, 2021 Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer +16 more
doaj +1 more source
Biology, 2021 (1) Background: Tumors of the peritoneal serosa are called peritoneal carcinosis. Their origin may be primary by primitive involvement of the peritoneum (peritoneal pseudomyxoma, peritoneal mesothelioma, etc.). This damage to the peritoneum can also be a
Niki Christou +7 more
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Cancer & Metabolism, 2022 Background Resistance to chemotherapeutic drugs is a key factor for cancer recurrence and metastases in head and neck cancer (HNC). Cancer stem cells (CSCs) in tumors have self-renewal, differentiation, and higher drug resistance capabilities, resulting ...
Wan-Hsuan Sun +4 more
doaj +1 more source
Progress in Progression? [PDF]
Journal of the American Society of Nephrology, 2010 Diabetic nephropathy is the major cause of ESRD in the United States.1 Unfortunately, only angiotensin-converting enzyme inhibitors or angiotensin type 1 receptor blockers are registered for slowing the progression of diabetic nephropathy—but they do not halt progression.2–5 Given that diabetic nephropathy costs the health care system close to $30 ...
openaire +1 more source
Tumor Hybrid Cells: Nature and Biological Significance
Frontiers in Cell and Developmental Biology, 2022 Metastasis is the leading cause of cancer death and can be realized through the phenomenon of tumor cell fusion. The fusion of tumor cells with other tumor or normal cells leads to the appearance of tumor hybrid cells (THCs) exhibiting novel properties ...
Maria S. Tretyakova +4 more
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Tumorigenicity of IL-1α– and IL-1β–Deficient Fibrosarcoma Cells
Neoplasia: An International Journal for Oncology Research, 2008 Analyzing the growth of fibrosarcoma lines derived from IL-1α–, IL-1β–, or IL-1αβ–knockout (−/−) mice in the immunocompetent host revealed that tumor-derived IL-1α and IL-1β exert strong and opposing effects on immune response induction, which prohibited
Irina Nazarenko +9 more
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The miR-17-92 cluster: Yin and Yang in human cancers
Cancer Treatment and Research Communications, 2022 MicroRNAs (miRNAs) are non-coding RNAs which modulate gene expression via multiple post-transcriptional mechanisms. They are involved in a variety of biological processes, including cell proliferation, metastasis, metabolism, tumorigenesis, and apoptosis.
Wenyuan Zhao +3 more
doaj +1 more source
, 2023 Background: Identifying a meaningful progression metric for Parkinson’s disease (PD) that reflects heterogeneity remains a challenge. Objective: To assess the frequency and baseline predictors of progression to clinically relevant motor and non-motor PD ...
Galasko, Douglas +11 more
core +1 more source