Results 1 to 10 of about 131,481 (208)

Alteration of the cortical actin cytoskeleton deregulates Ca2+ signaling, monospermic fertilization, and sperm entry. [PDF]

PLoS ONE, 2008
BackgroundWhen preparing for fertilization, oocytes undergo meiotic maturation during which structural changes occur in the endoplasmic reticulum (ER) that lead to a more efficient calcium response. During meiotic maturation and subsequent fertilization,
A Puppo, Jong T Chun, Giovanni Gragnaniello, Ezio Garante, Luigia Santella   +4 more
doaj   +1 more source

When fat is not bad: the regulation of actin dynamics by phospholipid signaling molecules

Frontiers in Plant Science, 2014
The actin cytoskeleton plays a key role in the plant morphogenesis and is involved in polar cell growth, movement of subcellular organelles, cell division, and plant defense.
Roman ePleskot, Přemysl ePejchar, Christopher J Staiger, Martin ePotocký   +3 more
doaj   +1 more source

Dynamin as a Mover and Pincher during Cell Migration and Invasion [PDF]

, 2006
The large GTPase dynamin, long known for its role in endocytosis, has most recently been implicated as a facilitator of cell migration and invasion. Recent observations link dynamin to the cycle of membrane expansion and retraction essential for cell ...
Kruchten, Anne E., McNiven, Mark A.
core   +2 more sources

Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton

Nature Communications, 2023
The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However, as mechanical
Sorosh Amiri, Camelia Muresan, Xingbo Shang, Clotilde Huet-Calderwood, Martin A. Schwartz, David A. Calderwood, Michael Murrell   +6 more
doaj   +1 more source

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

Frontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer, Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Max Krecke, Andrea Michela Biolato, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas   +16 more
doaj   +1 more source

RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry [PDF]

, 2018
Ciliopathies are a group of genetically heterogeneous disorders, characterized by defects in cilia genesis or maintenance. Mutations in the RPGR gene and its interacting partners, RPGRIP1 and RPGRIP1L, cause ciliopathies, but the function of their ...
Aguirre, Anselme, Aravind, Beales, Bergen, Berger, Berson, Billaud, Burnside, Burridge, Cahalan, Carroll, Chapman, Cossart, Ferreira, Ferreira, Fuchs, Habas, He, Hildebrandt, Hogan, Imanishi, Jacobson, Johnson, Kaibuchi, Katsanis, Kaykas, Kelley, Khaliq, Khanna, Khanna, Kroes, Lewis, Li, Li, Li, MacDonald, MacDonald, Meyer, Mitchell, Nelson, Nishina, Nusse, Prevarskaya, Putney, Ridley, Roepman, Rosado, Rüther, Rüther, Sage, Schermer, Schneider-Maunoury, Shu, Stainier, Tolwinski, Torban, Vaudin, Vervoort, Vesque, Wallingford, Wittinghofer, Wolfrum, Wright, Wright, Wright, Wright, Wright, Zrenner   +68 more
core   +3 more sources

A one-step procedure to probe the viscoelastic properties of cells by Atomic Force Microscopy [PDF]

, 2018
The increasingly recognised importance of viscoelastic properties of cells in pathological conditions requires rapid development of advanced cell microrheology technologies.
Chim, Ya Hua, Mason, Louise M., Olson, Michael F., Rath, Nicola, Tassieri, Manlio, Yin, Huabing   +5 more
core   +2 more sources

Stress relaxation in F-actin solutions by severing

, 2019
Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of actin-associated proteins that control cross-linking, polymerization and force generation in ...
Arzash, S., Feng, J., Gardel, M. L., MacKintosh, F. C., McCall, P. M.   +4 more
core   +1 more source

Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: Cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells [PDF]

, 2006
Bovine papillomaviruses (BPVs) are oncogenic viruses. In cattle, BPV-1/2 is associated with urinary bladder cancer and BPV-4 with upper GI tract cancer. BPV E5 is a small hydrophobic protein localised in the endoplasmic reticulum (ER) and Golgi apparatus
Anderson, Araibi, Ashrafi, Ashrafi, Barbara Marchetti, Brad Ozanne, Burnett, Campo, Carragher, DiMaio, Emmanuella Tsirimonaki, Faccini, Fackler, Frame, Frame, Frame, Frame, G. Hossein Ashrafi, Geiger, Hennigan, Jackson, Jaggar, Jarrett, Kasper, Lu, Lynn McGarry, M. Saveria Campo, Marchetti, Nobes, Nunbhakdi-Craig, O’Brien, O’Brien, O’Brien, Pennie, Robina Ullah, Schapiro, Schiller, Scott, Suprynowicz, zur Hausen   +39 more
core   +1 more source

Organization and Regulation of the Actin Cytoskeleton in the Pollen Tube

Frontiers in Plant Science, 2015
Proper organization of the actin cytoskeleton is crucial for pollen tube growth. However, the precise mechanisms by which the actin cytoskeleton regulates pollen tube growth remain to be further elucidated.
Xiaolu eQu, Yuxiang eJiang, Ming eChang, Xiaonan eLiu, Ruihui eZhang, Shanjin eHuang   +5 more
doaj   +1 more source