Results 1 to 10 of about 181,480 (263)

When fat is not bad: the regulation of actin dynamics by phospholipid signaling molecules

open access: yesFrontiers in Plant Science, 2014
The actin cytoskeleton plays a key role in the plant morphogenesis and is involved in polar cell growth, movement of subcellular organelles, cell division, and plant defense.
Roman ePleskot   +3 more
doaj   +1 more source

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

open access: yesFrontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer   +16 more
doaj   +1 more source

Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton

open access: yesNature Communications, 2023
The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However, as mechanical
Sorosh Amiri   +6 more
doaj   +1 more source

Organization and Regulation of the Actin Cytoskeleton in the Pollen Tube

open access: yesFrontiers in Plant Science, 2015
Proper organization of the actin cytoskeleton is crucial for pollen tube growth. However, the precise mechanisms by which the actin cytoskeleton regulates pollen tube growth remain to be further elucidated.
Xiaolu eQu   +5 more
doaj   +1 more source

NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation

open access: yesCell Communication and Signaling
Macroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Yuan Dong, Chengshi Quan
doaj   +1 more source

Wnt signalling and the actin cytoskeleton [PDF]

open access: yesOncogene, 2006
The tumour suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumours. APC binds to beta-catenin, a key component of the Wnt signalling pathway, and induces its degradation. In addition to this role, there is increasing evidence for additional roles of APC, including the organization of cytoskeletal networks. APC
T, Akiyama, Y, Kawasaki
openaire   +2 more sources

T lymphocyte migration: an action movie starring the actin and associated actors

open access: yesFrontiers in Immunology, 2015
The actin cytoskeleton is composed of a dynamic filament meshwork that builds the architecture of the cell to sustain its fundamental properties. This physical structure is characterized by a continuous remodeling, which allows cells to accomplish ...
Loïc eDupré   +4 more
doaj   +1 more source

An actin‐based cytoskeleton in archaea [PDF]

open access: yesMolecular Microbiology, 2011
Summary In eukaryotic and bacterial cells, spatial organization is dependent upon cytoskeletal filaments. Actin is a main eukaryotic cytoskeletal element, involved in key processes such as cell shape determination, mechanical force generation and cytokinesis.
Thijs J G, Ettema   +2 more
openaire   +2 more sources

EFFECT OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES ON CYTOSKELETON STRUCTURE AND MIGRATION ACTIVITY OF HUMAN ENDOTHELIAL CELLS

open access: yesМедицинская иммунология, 2017
There is a growing body of data about the cytopathic effect of bacterial arginine deiminase on human endothelial cells, but the precise mechanisms of endothelial dysfunction caused by the activity of the enzyme remain poorly understood.
E. A. Starikova   +5 more
doaj   +1 more source

Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo

open access: yesEuropean Journal of Cell Biology, 2022
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must be finely tuned, both in space and time, to fulfill key cellular functions
Clémentine Rouyère   +3 more
doaj   +1 more source

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