RACK1 promotes Shigella flexneri actin-mediated invasion, motility, and cell-to-cell spreading
iScience, 2023 Summary: Shigella flexneri is an intracellular bacterium that hijacks the host actin cytoskeleton to invade and disseminate within the colonic epithelium.
Karla N. Valenzuela-Valderas +8 more
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Getting cells into shape by calcium-dependent actin cross-linking proteins
Frontiers in Cell and Developmental Biology, 2023 The actin cytoskeleton represents a highly dynamic filament system providing cell structure and mechanical forces to drive a variety of cellular processes.
Franziska Lehne, Sven Bogdan
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IEEE Access, 2022 Actin cytoskeleton morphology is able to affect and reflect the cellular mechanical properties. However, due to the lack of efficient approaches to quantifying actin cytoskeleton and mechanical properties, the study of mechanotransduction dynamics is ...
Yi Liu +3 more
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Role of actin cytoskeleton in the organization and function of ionotropic glutamate receptors
Current Research in Structural Biology, 2021 Neural networks with precise connection are compulsory for learning and memory. Various cellular events occur during the genesis of dendritic spines to their maturation, synapse formation, stabilization of the synapse, and proper signal transmission. The
Priyanka Dutta +3 more
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Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation
Frontiers in Immunology, 2021 A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa +3 more
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LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton
Frontiers in Cell and Developmental Biology, 2021 LUZP1 is a centrosomal and actin cytoskeleton-localizing protein that regulates both ciliogenesis and actin filament bundling. As the cytoskeleton and cilia are implicated in metastasis and tumor suppression, we examined roles for LUZP1 in the context of
Laura Bozal-Basterra +12 more
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Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. [PDF]
, 2010 Filamin and Cortexillin are F-actin crosslinking proteins in Dictyostelium discoideum allowing actin filaments to form three-dimensional networks. GAPA, an IQGAP related protein, is required for cytokinesis and localizes to the cleavage furrow during ...
Bhagyashri Burgute +24 more
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Actin Cytoskeleton Affects Schwann Cell Migration and Peripheral Nerve Regeneration
Frontiers in Physiology, 2018 Actin cytoskeleton regulates many essential biological functions, including cellular development, shape, polarity, and motility. The organization of actin cytoskeleton has also been associated with numerous physiological and pathological conditions, for ...
Yaxian Wang +3 more
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Quantitative Investigation of the Link between Actin Cytoskeleton Dynamics and Cellular Behavior
Micromachines, 2022 Actin cytoskeleton reorganization, which is governed by actin-associated proteins, has a close relationship with the change of cell biological behavior. However, a perceived understanding of how actin mechanical property links to cell biological property
Ying Li, Xiaoru Zhuang, Fuzhou Niu
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Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling [PDF]
, 2004 The role of the actin cytoskeleton in regulating membrane protein trafficking is complex and depends on the cell type and protein being examined. Using the epididymis as a model system in which luminal acidification is crucial for sperm maturation and ...
Pastor-Soler, Nuria +8 more
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