Results 41 to 50 of about 369,220 (302)

Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]

open access: yes, 2014
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Mulvihill, Daniel P.   +2 more
core   +1 more source

Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton

open access: yesFrontiers in Molecular Biosciences, 2022
Platelets are anucleate cells that are essential for hemostasis and wound healing. Upon activation of the cell surface receptors by their corresponding extracellular ligands, platelets undergo rapid shape change driven by the actin cytoskeleton; this ...
Enoli De Silva   +8 more
doaj   +1 more source

Mythical origins of the actin cytoskeleton

open access: yesCurrent Opinion in Cell Biology, 2021
The origin of the eukaryotic cell is one of the greatest mysteries in modern biology. Eukaryotic-wide specific biological processes arose in the lost ancestors of eukaryotes. These distinctive features, such as the actin cytoskeleton, define what it is to be a eukaryote.
Caner Akıl   +8 more
openaire   +3 more sources

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins

open access: yesBiology Open, 2016
Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample preparation protocols for SRM are rather anecdotal and still being optimized.
Daniela Leyton-Puig   +5 more
doaj   +1 more source

A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae [PDF]

open access: yes, 2001
In vivo time-lapse microscopy reveals that the number of peroxisomes in Saccharomyces cerevisiae cells is fairly constant and that a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process.
Marlene van den Berg   +11 more
core   +2 more sources

When fat is not bad: the regulation of actin dynamics by phospholipid signaling molecules

open access: yesFrontiers in Plant Science, 2014
The actin cytoskeleton plays a key role in the plant morphogenesis and is involved in polar cell growth, movement of subcellular organelles, cell division, and plant defense.
Roman ePleskot   +3 more
doaj   +1 more source

Alteration of the cortical actin cytoskeleton deregulates Ca2+ signaling, monospermic fertilization, and sperm entry. [PDF]

open access: yesPLoS ONE, 2008
BackgroundWhen preparing for fertilization, oocytes undergo meiotic maturation during which structural changes occur in the endoplasmic reticulum (ER) that lead to a more efficient calcium response. During meiotic maturation and subsequent fertilization,
A Puppo   +4 more
doaj   +1 more source

Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton [PDF]

open access: yes, 2010
Apicomplexan parasites within the genus <i>Theileria</i> have the ability to induce continuous proliferation and prevent apoptosis of the infected bovine leukocyte.
Weir, W.   +8 more
core   +1 more source

Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton

open access: yesNature Communications, 2023
The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However, as mechanical
Sorosh Amiri   +6 more
doaj   +1 more source

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

open access: yesFrontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer   +16 more
doaj   +1 more source

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