Results 21 to 30 of about 625,356 (301)

Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation

Frontiers in Immunology, 2021
A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa, Federica Penco, Stefano Volpi, Marco Gattorno   +3 more
doaj   +1 more source

Dendritic Spines in Alzheimer’s Disease: How the Actin Cytoskeleton Contributes to Synaptic Failure

International Journal of Molecular Sciences, 2020
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by Aβ-driven synaptic dysfunction in the early phases of pathogenesis. In the synaptic context, the actin cytoskeleton is a crucial element to maintain the dendritic spine ...
S. Pelucchi, R. Stringhi, Elena Marcello
semanticscholar   +1 more source

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton

Frontiers in Cell and Developmental Biology, 2021
LUZP1 is a centrosomal and actin cytoskeleton-localizing protein that regulates both ciliogenesis and actin filament bundling. As the cytoskeleton and cilia are implicated in metastasis and tumor suppression, we examined roles for LUZP1 in the context of
Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Natalia Martín-Martín, Amaia Ercilla, Amaia Ercilla, Jose A. Rodríguez, Arkaitz Carracedo, Arkaitz Carracedo, Arkaitz Carracedo, Arkaitz Carracedo, James D. Sutherland, Rosa Barrio   +12 more
doaj   +1 more source

A functional link between the actin cytoskeleton and lipid rafts during budding of filamentous influenza virions [PDF]

, 2002
Morphogenesis of influenza virus is a poorly understood process that produces two types of enveloped virion: approximately 100-nm spheres and similar diameter filaments that reach 20 microm in length. Spherical particles assemble at plasma membrane lipid
Paul Digard, Simpson-Holley, Martha, McCauley, John, Debra Elton, Ellis, Darren, John McCauley, Darren Ellis, Digard, Paul, Martha Simpson-Holley, Fisher, Dawn, Elton, Debra, Dawn Fisher   +11 more
core   +1 more source

Actin Cytoskeleton Affects Schwann Cell Migration and Peripheral Nerve Regeneration

Frontiers in Physiology, 2018
Actin cytoskeleton regulates many essential biological functions, including cellular development, shape, polarity, and motility. The organization of actin cytoskeleton has also been associated with numerous physiological and pathological conditions, for ...
Yaxian Wang, Qianqian Shan, Jiacheng Pan, Sheng Yi   +3 more
doaj   +1 more source

Quantitative Investigation of the Link between Actin Cytoskeleton Dynamics and Cellular Behavior

Micromachines, 2022
Actin cytoskeleton reorganization, which is governed by actin-associated proteins, has a close relationship with the change of cell biological behavior. However, a perceived understanding of how actin mechanical property links to cell biological property
Ying Li, Xiaoru Zhuang, Fuzhou Niu
doaj   +1 more source

Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. [PDF]

, 2010
Filamin and Cortexillin are F-actin crosslinking proteins in Dictyostelium discoideum allowing actin filaments to form three-dimensional networks. GAPA, an IQGAP related protein, is required for cytokinesis and localizes to the cleavage furrow during ...
Bhagyashri Burgute, Müller Rolf, Müller, Rolf, Schleicher Michael, Daniela Rieger, Rieger, Daniela, Angelika A Noegel, Faix Jan, Noegel, Angelika A., Angelika A. Noegel, Rivero Francisco, Rolf Müller, Faix, Jan, Schleicher, Michael, Burgute Bhagyashri, Francisco Rivero, Subhanjan Mondal, Mondal, Subhanjan, Rieger Daniela, Rivero, Francisco, Michael Schleicher, Burgute, Bhagyashri, Mondal Subhanjan, Noegel Angelika A., Jan Faix   +24 more
core   +2 more sources

Visualization and Manipulation of Actin Cytoskeleton with Small-Molecular Probes [PDF]

, 2020
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell. Here, in order to dissect the complex mechanisms of actin-related cellular functions, we introduce two powerful tools based on a new class
Keisuke, Ikawa, Tetsuo, Nagano, Yusuke, Nomura, Chika, Okimura, Kaoru, Sugimura, Kenjiro, Hanaoka, Toru, Komatsu, Yoshiaki, Iwadate, Daisuke, Asanuma, Kenzo, Hirose, Tasuku, Ueno, Shin-nosuke, Uno, Mako, Kamiya, Yasuteru, Urano, Takeru, Takagi   +14 more
core   +2 more sources

Dynamics of the Actin Cytoskeleton at Adhesion Complexes

Biology, 2021
The shape of cells is altered to allow cells to adapt to their changing environments, including responding to internally generated and externally applied force. Force is sensed by cell surface adhesion proteins that are enriched in sites where cells bind
Nicholas M. Cronin, Kris A. DeMali
doaj   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Aszodi, Attila, Emanuel Rognoni (124910), Rehberg, Markus, Montanez Eloi, Eloi Montanez (124926), Rognoni Emanuel, Franco, C.A., Emanuel Rognoni, Neto, F, Aszodi Attila, Neto, Filipa, Claudio A. Franco, Rehberg Markus, Alessia Fraccaroli, Fraccaroli Alessia, Gerhardt Holger, Gerhardt, H, Roland Wedlich-Söldner, Montanez, E., Rognoni, E., Montanez, E, Claudio A. Franco (124909), Wedlich-Söldner, Roland, Fraccaroli, A., Filipa, N., Franco Claudio A., Attila Aszodi, Gerhardt, Holger, Neto, F., Alessia Fraccaroli (124908), Holger Gerhardt (124923), Montanez, Eloi, Filipa Neto (124912), Fraccaroli, Alessia, Aszodi, A., Rognoni, E, Claudio A Franco, Filipa Neto, Franco, Claudio A., Wedlich-Söldner Roland, Ulrich Pohl (124920), Markus Rehberg, Pohl, U, Aszodi, A, Wedlich-Söldner, R., Neto Filipa, Pohl, U., Eloi Montanez, Pohl Ulrich, Franco, C., Wedlich-Söldner, R, Holger Gerhardt, Ulrich Pohl, Franco, CA, Pohl, Ulrich, Markus Rehberg (124914), Rehberg, M., Gerhardt, H., Roland Wedlich-Söldner (124918), Rognoni, Emanuel, Attila Aszodi (124916), Fraccaroli, A, Rehberg, M   +62 more
core   +2 more sources