Results 31 to 40 of about 625,356 (301)

Bending over backwards: BAR proteins and the actin cytoskeleton in mammalian receptor-mediated endocytosis

open access: yesEuropean Journal of Cell Biology, 2022
The role of the actin cytoskeleton during receptor-mediated endocytosis (RME) has been well characterized in yeast for many years. Only more recently has the interplay between the actin cytoskeleton and RME been extensively explored in mammalian cells ...
Garett Armstrong, Michael F. Olson
doaj   +1 more source

Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling [PDF]

open access: yes, 2004
The role of the actin cytoskeleton in regulating membrane protein trafficking is complex and depends on the cell type and protein being examined. Using the epididymis as a model system in which luminal acidification is crucial for sperm maturation and ...
Pastor-Soler, Nuria   +8 more
core   +1 more source

The Actin Cytoskeleton and Actin-Based Motility

open access: yesCold Spring Harbor Perspectives in Biology, 2018
SUMMARY The actin cytoskeleton – a collection of actin filaments with their accessory and regulatory proteins – is the primary force-generating machinery in the cell.
T. Svitkina
semanticscholar   +1 more source

Cell wall stress depolarizes cell growth via hyperactivation of RHO1 [PDF]

open access: yes, 1999
Cells sense and physiologically respond to environmental stress via signaling pathways. Saccharomyces cerevisiae cells respond to cell wall stress by transiently depolarizing the actin cytoskeleton.
Hall, M. N.   +5 more
core   +1 more source

Physical mechanism of the compressive response of F-actin networks: significance of crosslinker unbinding events

open access: yesTheoretical and Applied Mechanics Letters, 2014
A model of crosslinker unbinding is implemented in a highly coarse-grained granular model of F-actin cytoskeleton. We employ this specific granular model to study the mechanisms of the compressive responses of F-actin networks.
Tong Li   +3 more
doaj   +1 more source

Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]

open access: yes, 2009
Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
core   +1 more source

Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation. [PDF]

open access: yes, 2012
Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet-Biedl syndrome proteins form a complex that is important for several cytoskeleton-related processes such as ciliogenesis, cell migration and ...
D Jenkins   +20 more
core   +1 more source

Modulation of TMEM16A-Channel Activity as Ca2+ Activated Cl− Conductance via the Interaction With Actin Cytoskeleton in Murine Portal Vein

open access: yesJournal of Pharmacological Sciences, 2014
.: TMEM16A is a major component of Ca2+-activated Cl− channel (CaCC) conductance in murine portal vein smooth muscle cells (mPVSMCs). Here, the regulation of CaCC activity by the actin cytoskeleton was examined in mPVSMCs.
Junya Ohshiro   +3 more
doaj   +1 more source

An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]

open access: yes, 2014
Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding   +9 more
core   +1 more source

The Actin Cytoskeleton as an Active Adaptive Material

open access: yesAnnual Review of Condensed Matter Physics, 2019
Actin is the main protein used by biological cells to adapt their structure and mechanics to their needs. Cellular adaptation is made possible by molecular processes that strongly depend on mechanics.
Shiladitya Banerjee   +2 more
semanticscholar   +1 more source

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