Results 31 to 40 of about 131,481 (208)

The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer [PDF]

open access: yes, 2014
The contractile actin-myosin cytoskeleton provides much of the force required for numerous cellular activities such as motility, adhesion, cytokinesis and changes in morphology.
AP Somlyo   +62 more
core   +1 more source

Physical mechanism of the compressive response of F-actin networks: significance of crosslinker unbinding events

open access: yesTheoretical and Applied Mechanics Letters, 2014
A model of crosslinker unbinding is implemented in a highly coarse-grained granular model of F-actin cytoskeleton. We employ this specific granular model to study the mechanisms of the compressive responses of F-actin networks.
Tong Li   +3 more
doaj   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

open access: yes, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick   +5 more
core   +4 more sources

Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]

open access: yes, 2013
Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong   +10 more
core   +2 more sources

Modulation of TMEM16A-Channel Activity as Ca2+ Activated Cl− Conductance via the Interaction With Actin Cytoskeleton in Murine Portal Vein

open access: yesJournal of Pharmacological Sciences, 2014
.: TMEM16A is a major component of Ca2+-activated Cl− channel (CaCC) conductance in murine portal vein smooth muscle cells (mPVSMCs). Here, the regulation of CaCC activity by the actin cytoskeleton was examined in mPVSMCs.
Junya Ohshiro   +3 more
doaj   +1 more source

Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]

open access: yes, 2016
Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core   +2 more sources

Sphingosine-1-phosphate Treatment Improves Cryopreservation Efficiency in Human Mesenchymal Stem Cells

open access: yesLife, 2023
The actin cytoskeleton plays a crucial role not only in maintaining cell shape and viability but also in homing/engraftment properties of mesenchymal stem cells (MSCs), a valuable source of cell therapy.
Seong-Ju Oh   +6 more
doaj   +1 more source

Focal adhesions as mechanosensors: the two-spring model [PDF]

open access: yes, 2004
Adhesion-dependent cells actively sense the mechanical properties of their environment through mechanotransductory processes at focal adhesions, which are integrin-based contacts connecting the extracellular matrix to the cytoskeleton.
Schwarz, Ulrich S.   +2 more
core   +2 more sources

Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton

open access: yesFrontiers in Molecular Biosciences, 2022
Platelets are anucleate cells that are essential for hemostasis and wound healing. Upon activation of the cell surface receptors by their corresponding extracellular ligands, platelets undergo rapid shape change driven by the actin cytoskeleton; this ...
Enoli De Silva   +8 more
doaj   +1 more source

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins

open access: yesBiology Open, 2016
Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample preparation protocols for SRM are rather anecdotal and still being optimized.
Daniela Leyton-Puig   +5 more
doaj   +1 more source

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