Results 31 to 40 of about 181,480 (263)

The actin cytoskeleton in presynaptic assembly [PDF]

open access: yesCell Adhesion & Migration, 2013
Dramatic morphogenetic processes underpin nearly every step of nervous system development, from initial neuronal migration and axon guidance to synaptogenesis. Underlying this morphogenesis are dynamic rearrangements of cytoskeletal architecture. Here we discuss the roles of the actin cytoskeleton in the development of presynaptic terminals, from the ...
Jessica C, Nelson   +2 more
openaire   +2 more sources

Ultrastructure of the actin cytoskeleton [PDF]

open access: yesCurrent Opinion in Cell Biology, 2018
The actin cytoskeleton is the primary force-generating machinery in the cell, which can produce pushing (protrusive) forces using energy of actin polymerization and pulling (contractile) forces via sliding of bipolar filaments of myosin II along actin filaments, as well as perform other key functions.
openaire   +2 more sources

Modulation of TMEM16A-Channel Activity as Ca2+ Activated Cl− Conductance via the Interaction With Actin Cytoskeleton in Murine Portal Vein

open access: yesJournal of Pharmacological Sciences, 2014
.: TMEM16A is a major component of Ca2+-activated Cl− channel (CaCC) conductance in murine portal vein smooth muscle cells (mPVSMCs). Here, the regulation of CaCC activity by the actin cytoskeleton was examined in mPVSMCs.
Junya Ohshiro   +3 more
doaj   +1 more source

Sphingosine-1-phosphate Treatment Improves Cryopreservation Efficiency in Human Mesenchymal Stem Cells

open access: yesLife, 2023
The actin cytoskeleton plays a crucial role not only in maintaining cell shape and viability but also in homing/engraftment properties of mesenchymal stem cells (MSCs), a valuable source of cell therapy.
Seong-Ju Oh   +6 more
doaj   +1 more source

Novel Actin Cytoskeleton. Actin Tubules.

open access: yesCell Structure and Function, 2000
In spores of Dictyostelium discoideum three actin filaments are bundled to form a novel tubular structure and the tubules are then organized into rods. These tubular structures we will term actin tubules. Actin tubules are reconstructed from the supernatant of spore homogenates, while the usual actin filaments were bundled after incubation of ...
Sameshima, Masazumi   +4 more
openaire   +3 more sources

The Actin Cytoskeleton and Actin-Based Motility [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2018
The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of ...
openaire   +2 more sources

Podocytopathy: The role of actin cytoskeleton

open access: yesBiomedicine & Pharmacotherapy, 2022
Renal injury and the development of albuminuria are tightly connected with the loss of podocytes. Podocyte damages cause proteinuric renal diseases since podocyte foot processes (FP) and their interposed slit diaphragms (SD) are the final barriers against protein loss.
Elham Ahmadian   +6 more
openaire   +2 more sources

Alteration of the cortical actin cytoskeleton deregulates Ca2+ signaling, monospermic fertilization, and sperm entry. [PDF]

open access: yesPLoS ONE, 2008
BackgroundWhen preparing for fertilization, oocytes undergo meiotic maturation during which structural changes occur in the endoplasmic reticulum (ER) that lead to a more efficient calcium response. During meiotic maturation and subsequent fertilization,
A Puppo   +4 more
doaj   +1 more source

Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton

open access: yesFrontiers in Molecular Biosciences, 2022
Platelets are anucleate cells that are essential for hemostasis and wound healing. Upon activation of the cell surface receptors by their corresponding extracellular ligands, platelets undergo rapid shape change driven by the actin cytoskeleton; this ...
Enoli De Silva   +8 more
doaj   +1 more source

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins

open access: yesBiology Open, 2016
Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample preparation protocols for SRM are rather anecdotal and still being optimized.
Daniela Leyton-Puig   +5 more
doaj   +1 more source

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