Results 51 to 60 of about 206,697 (309)

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

Frontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer, Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Max Krecke, Andrea Michela Biolato, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas   +16 more
doaj   +1 more source

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy [PDF]

, 2013
BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function.
Benz, PM, Frantz, Stefan, Merkel, CJ, Offner, Kristin, Fleming, Ingrid, Feller, Stephan M., Renné, T, Gambaryan, Stepan, Unger, A, Linke, Wolfgang A., Fischer, T, Merkel, Carla J., Bayer, B, Schuh, K, Benz, Peter M., Wagner, Helga, Ullrich, Melanie, Linke, WA, Bayer, Barbara, Ullrich, M, Offner, K, Renné, Thomas, Abeßer, M, Ursitti, Jeanine A., Frantz, S, Adham, Ibrahim M., Unger, Andreas, Adham, IM, Feller, SM, Fischer, Tobias, Wagner, H, Abeßer, Marco, Schuh, Kai, Gambaryan, S, Fleming, I, Ursitti, JA   +35 more
core   +1 more source

Oscillatory Dynamics of the Actin Cytoskeleton [PDF]

, 2022
The actin cytoskeleton is ubiquitously distributed among eukaryotic organisms and determines the shape and the movement of eukaryotic cells. In single migratory cells, rapid and localized actin polymerization often follows an external stimulus, engaging migration towards or away from the stimulus.
Westendorf, Christian, Bodenschatz, Eberhard, Georg-August-Universität Göttingen, Bodenschatz, Eberhard, Steinbock, Oliver   +4 more
openaire   +3 more sources

Role of the cytoskeleton in melanogenesis [PDF]

, 2023
openThis thesis presents a critical analysis of the scientific article entitled “PRP4 Promotes Skin Cancer by Inhibiting Production of Melanin, Blocking Influx of Extracellular Calcium, and Remodeling Cell Actin Cytoskeleton”.
ZANON, BENEDETTA
core  

Organization and Regulation of the Actin Cytoskeleton in the Pollen Tube

Frontiers in Plant Science, 2015
Proper organization of the actin cytoskeleton is crucial for pollen tube growth. However, the precise mechanisms by which the actin cytoskeleton regulates pollen tube growth remain to be further elucidated.
Xiaolu eQu, Yuxiang eJiang, Ming eChang, Xiaonan eLiu, Ruihui eZhang, Shanjin eHuang   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale [PDF]

, 2014
Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved.
Sobczyk, Grzegorz J., Weijer, Cornelis J.; id_orcid, Wang, Jun   +2 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Development of a Tool to Visualize F-actin and Organelle Contact Sites [PDF]

, 2022
reservedThe actin cytoskeleton plays a critical role in not only cell shape and motility, but also organelle function. Growing evidence reveals the importance of actin dynamics at organelle membranes in mediating cellular processes and homeostasis.
CHEN, SERENA
core  

NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation

Cell Communication and Signaling
Macroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Yuan Dong, Chengshi Quan
doaj   +1 more source