Results 71 to 80 of about 206,697 (309)
The actin cytoskeleton in ageing and apoptosis [PDF]
FEMS Yeast Research, 2005 Regulated cell death, or apoptosis, has evolved to fulfil a myriad of functions amongst multicellular organisms. It is now apparent that programmed cell death occurs in unicellular organisms such as yeast. In yeast, as in higher eukaryotes, the actin cytoskeleton is an essential component of a number of cellular activities, and many of the regulatory ...
Campbell W, Gourlay, Kathryn R, Ayscough
openaire +2 more sources
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The dynamic status of actin in the regulation of environmental sensing and homeostatic control in Saccharomyces cerevisiae [PDF]
, 2014 Actin is a highly conserved protein in eukaryotes which forms dynamic cytoskeletal structures. Rapid remodeling of actin filaments is important for the regulation of a broad range of critical cellular processes.
Smethurst, Daniel George Jan
core
Interactions between plant endomembrane systems and the actin cytoskeleton
Frontiers in Plant Science, 2015 Membrane trafficking, organelle movement and morphogenesis in plant cells are mainly controlled by the cytoskeleton. Not all proteins that regulate the actin cytoskeleton and membrane dynamics in animal systems have functional homologues in plants ...
Pengwei eWang, Patrick J. Hussey
doaj +1 more source
A novel function of twins, B subunit of protein phosphatase 2A, in regulating actin polymerization. [PDF]
PLoS ONE, 2017 Actin is an important component of the cytoskeleton and its polymerization is delicately regulated by several kinases and phosphatases. Heterotrimeric protein phosphatase 2A (PP2A) is a potent phosphatase that is crucial for cell proliferation, apoptosis,
Po-An Yeh, Ching-Jin Chang
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Comprehensive contribution of filament thickness and crosslinker failure to the rheological property of F-actin cytoskeleton [PDF]
, 2015 Rheological property of F-actin cytoskeleton is significant to the restructuring of cytoskeleton under a variety of cell activities. This study numerically validates the rheological property of F-actin cytoskeleton is not only a result of kinetic energy ...
Yarlagadda, Prasad K. +7 more
core +1 more source
Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia
BMC Immunology, 2010 Background Most in vivo studies that have addressed the role of actin dynamics in NADPH oxidase function in phagocytes have used toxins to modulate the polymerization state of actin and mostly effects on actin has been evaluated by end point measurements
Rasmussen Izabela +5 more
doaj +1 more source
Actin Dynamics at the T Cell Synapse as Revealed by Immune-Related Actinopathies
Frontiers in Cell and Developmental Biology, 2021 The actin cytoskeleton is composed of dynamic filament networks that build adaptable local architectures to sustain nearly all cellular activities in response to a myriad of stimuli. Although the function of numerous players that tune actin remodeling is
Loïc Dupré +11 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source