Results 91 to 100 of about 206,697 (309)

RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes [PDF]

open access: yes, 2013
The role of the mRNA-binding protein human antigen R (HuR) in stabilization and translation of AU-rich elements (ARE) containing mRNAs is well established.
Eberhardt, Wolfgang   +3 more
core   +1 more source

Shielding of actin by the endoplasmic reticulum impacts nuclear positioning

open access: yesNature Communications, 2022
The nucleus connects to the actin cytoskeleton for nuclear movement in migrating cells. Here, the authors show that the endoplasmic reticulum shields actin cables to generate asymmetric nucleo-cytoskeleton connections for nuclear positioning.
Cátia Silva Janota   +7 more
doaj   +1 more source

Interactions of mitochondria with the actin cytoskeleton

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
Interactions between mitochondria and the cytoskeleton are essential for normal mitochondrial morphology, motility and distribution. While microtubules and their motors have been established as important factors for mitochondrial transport, emerging evidence indicates that mitochondria interact with the actin cytoskeleton in many cell types. In certain
Boldogh, Istvan R., Pon, Liza A.
openaire   +2 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1. [PDF]

open access: yes, 2014
Elevation of intracellular cAMP concentration has numerous vascular protective effects that are in part mediated via actin cytoskeleton-remodelling and subsequent regulation of gene expression. However, the mechanisms are incompletely understood. Here we
Sala-Newby GB   +6 more
core   +1 more source

The Role of Actin Cytoskeleton in Memory Formation in Amygdala

open access: yesFrontiers in Molecular Neuroscience, 2016
The central, lateral and basolateral amygdala nuclei are essential for the formation of long-term memories including emotional and drug-related memories. The study of cellular and molecular mechanisms underpinning memory in amygdala may shed light on the
Raphael eLamprecht
doaj   +1 more source

Endocytosis, Actin Cytoskeleton, and Signaling [PDF]

open access: yesPlant Physiology, 2004
Endocytosis is the internalization of plasma membrane proteins and lipids, extracellular molecules, fluids, particles, exosomes, viruses, and bacteria. Endocytic internalization is a conserved process for all eukaryotic cells that is required for diverse cellular functions.
Jozef, Samaj   +5 more
openaire   +2 more sources

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Cross-scale biophysics modelling of F-actin cytoskeleton in cell [PDF]

open access: yes, 2015
This thesis is a comparative study of the modelling of mechanical behaviours of F-actin cytoskeleton which is an important structural component in living cells.
Li, Tong
core  

Stabilization of the cortical cytoskeleton by the lipid raft-associated protein cap23 [PDF]

open access: yes, 2006
In the present work, we identified the lipid raft-associated protein Cap23 to be involved in several important neuronal functions like the organization of lipid raft platforms, the maturation and stabilization of the actin- and intermediate filament ...
Wacha, Stefan
core   +1 more source

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