Results 261 to 270 of about 6,463,095 (311)

Predicting progression-free survival in glioblastoma: influence of the perilesional oedema and white-matter disconnectome

open access: yes
Tariq M   +10 more
europepmc   +1 more source

Correlation of progression-free and post-progression survival with overall survival in advanced colorectal cancer

open access: yesAnnals of Oncology, 2013
Polychemotherapy and biological drugs have increased therapeutic options and outcomes of advanced colorectal cancer (CRC). We examined the relation between progression-free survival (PFS), post-progression survival (PPS) and overall survival (OS) in trials of modern (oxaliplatin- and irinotecan-based) chemotherapy alone or with targeted therapies for ...
Fausto Petrelli
exaly   +4 more sources
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Concordance index: Surrogacy of progression-free survival for overall survival

Contemporary Clinical Trials, 2021
In oncology clinical trials, the primary endpoint is often time to an event of clinical interest, e.g., time to disease progression or time to death. As a result, progression-free survival (PFS: the time from initiation of treatment till disease progression or death whichever occurs first) and overall survival (OS: the time from initiation of treatment
Yiwei, Fan, Guosheng, Yin
openaire   +2 more sources

Alternatives to the Kaplan–Meier estimator of progression-free survival

The International Journal of Biostatistics, 2020
Abstract Progression-free survival (PFS), defined as the time from randomization to progression of disease or death, has been indicated as an endpoint to support accelerated approval of certain cancer drugs by the U.S. FDA. The standard Kaplan–Meier (KM) estimator of PFS, however, can result in significantly biased estimates.
Zhang, Jenny J.   +3 more
openaire   +2 more sources

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