Results 91 to 100 of about 82,833 (333)

AMINN: Autoencoder-based Multiple Instance Neural Network Improves Outcome Prediction of Multifocal Liver Metastases [PDF]

arXiv, 2020
Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively unexplored in CRLM outcome prediction.
arxiv  

Description of a multifocal arrangement of asymmetric Kummer-beam optical vortices [PDF]

, 2019
In this work, an analytic expression is derived for the optical field generated by an off-axis Gaussian beam diffracted by a Discrete Vortex-Producing Lens. With this system, a multifocal arrangement of asymmetric optical vortices is obtained whose topological charge values change with the position along the optical axis. This scheme allows obtaining a
arxiv   +1 more source

Alopecia Areata: Pathogenesis, Diagnosis, and Therapies

MedComm, Volume 6, Issue 5, May 2025.
This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma, Tingrui Zhang, Fengze Miao, Jun Liu, Quangang Zhu, Zhongjian Chen, Zongguang Tai, Zhigao He   +7 more
wiley   +1 more source

Brainstem progressive multifocal leukoencephalopathy

European Journal of Neurology, 2020
AbstractBackground and purposeProgressive multifocal leukoencephalopathy (PML) is a severe infection caused by the polyomavirus JC that develops in the central nervous system (CNS) of immunosuppressed patients. The infection frequently starts in the brain hemispheres and can spread into other CNS regions such as the brainstem.
Gautier Breville, Igor J. Koralnik, Patrice H. Lalive, Patrice H. Lalive   +3 more
openaire   +4 more sources

Progressive Multifocal Leukoencephalopathy [PDF]

Journal of Multiple Sclerosis, 2013
Progressive multifocal leukoencephalopathy (PML) is a rare, myelin-damaging disease of the central nervous system (CNS) in a setting of immunosuppression that is superimposed by concurrent autoimmune diseases such as multiple sclerosis and AIDS or simultaneous administration of immune modulatory monoclonal antibody drugs such as natalizumab.
Chiedukam A. Adiele, Reginald C. Adiele
openaire   +2 more sources

The Use of Antimalarial Drugs against Viral Infection [PDF]

, 2020
In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new ...
D. Scaccabarozzi, D.P. Ilboudo, F. Perego, L. Signorini, P. Ferrante, S. D&apos, S. Delbue   +6 more
core   +1 more source

Progressive multifocal leukoencephalopathy

Neurology: Neuroimmunology & Neuroinflammation, 2019
Objective To characterize the risk factors, clinical course, and treatment of patients with progressive multifocal leukoencephalopathy (PML) diagnosed and followed over a 25-year epoch at 2 academic hospitals.
Pria Anand, G. Hotan, A. Vogel, N. Venna, F. Mateen   +4 more
semanticscholar   +1 more source

Safety and effectiveness of fingolimod in Japanese patients with multiple sclerosis: Results of a post‐marketing surveillance study

Clinical and Experimental Neuroimmunology, Volume 16, Issue 2, Page 118-131, May 2025.
Abstract Objective Fingolimod is the first oral sphingosine‐1‐phosphate receptor modulator approved in Japan for multiple sclerosis (MS). A large Japanese observational study of fingolimod in patients with MS was carried out to support its safety and effectiveness in a real‐world setting.
Noriko Sato, Koji Wakimoto, Kyoko Kato, Yutaka Susuta, Kengo Ueda, Yoshihisa Satou, Takayoshi Sasajima, Jun‐ichi Kira   +7 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

International Journal of General Medicine, 2009
Melissa G Ooi1, Peter J Kelly2, Michael Farrell3, Philip Murphy4, Peter O’Gorman11Department of Hematology; 2Department of Neurology, Mater Misericordiae Hospital, Dublin, Ireland; 3Department of Neuropathology; 4Department of Hematology ...
Melissa G Ooi, Peter J Kelly, Michael Farrell, Philip Murphy, Peter O’Gorman   +4 more
doaj  

Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis

Case Reports in Radiology, 2013
Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal ...
Guglielmo Manenti, Simone Altobelli, Marco Nezzo, Marco Antonicoli, Erald Vasili, Luca Neroni, Roberto Floris, Giovanni Simonetti   +7 more
doaj   +1 more source