Results 101 to 110 of about 82,833 (333)

Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient

Case Reports in Neurology, 2013
Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients.
Krisztina K. Johansen, Sverre H. Torp, Jana Rydland, Jan O. Aasly   +3 more
doaj   +1 more source

Signs of Psychosis Leading to a Diagnosis of Progressive Multifocal Leukoencephalopathy: A Case Report [PDF]

, 2019
Introduction: Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating process of the central nervous system that occurs in in the setting of severe immunocompromise.
Holt, Christina, MD, MSc, Walker, Bryan L   +1 more
core   +2 more sources

Four cases of progressive multifocal leukoencephalopathy in iatrogenic immunocompromised patients [PDF]

, 2020
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by John Cunningham Virus (JCV). We report four PML cases in immunocompromised patients, respectively treated with (1) Natalizumab, (2 ...
Banco M. A., Bianchi A., La Tona G., Portera E., Ragonese P., Realmuto S., Salemi G., Vazzoler G.   +7 more
core   +1 more source

Diagnostic Insighhts Into JC Virus–Infected Glial Cells: Intraoperative Cytopathological Analysis of Dot‐Shaped Inclusions Associated With PML‐NBs

Cytopathology, Volume 36, Issue 3, Page 281-284, May 2025.
This is the first case report describing the diagnostic value of dot‐shaped inclusions associated with promyelocytic leukaemia nuclear bodies (PML‐NBs) to define JC virus–infected glial cells in an intraoperative cytopathological diagnosis for progressive multifocal leukoencephalopathy (PML).
Nobuko Ujihira, Hideki Doi, Yukiko Shishido‐Hara   +2 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy (PML)

Rinsho Shinkeigaku, 2011
Progressive multifocal leukoencephalopathy (PML) is caused by reactivation of latently infected JCV when hosts' immune system is impaired by HIV infection, hematologic diseases, collagen diseases, immunemodulatory therapy and so on. PML was rare but HIV infection and Natalizumab have made it much more common while the prognosis is much better than ...
Yukiko Shishido-Hara, Hirohumi Sawa, Masahito Yamada, Masayuki Saijo, Souichi Nukuzuma, Shuji Kishida, Motohiro Yukishita, Kazuo Nagashima, Hidehiro Mizusawa   +8 more
openaire   +3 more sources

Thick distribution tails in models of cancer secondary tumors [PDF]

arXiv, 2018
Recent progress in microdissection and in DNA sequencing has enabled subsampling of multi-focal cancers in organs such as the liver in several hundred spots, helping to determine the pattern of mutations in each of these spots. This has led to the construction of genealogies of the primary, secondary, tertiary and so forth, foci of the tumor.
arxiv  

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 686-700, April 2025.
By applying the tensor model, we analysed lesion orientation and the directionality of lesion expansion/contraction in multiple sclerosis. Each lesion is summarized as an ellipsoid, and the tensor model is applied to calculate lesion anisotropy. From the top to the bottom white matter atlas, surface‐in gradient segmentation and venous atlas used in the
Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard   +9 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy therapy [PDF]

Journal of NeuroVirology, 2014
Progressive multifocal leukoencephalopathy (PML) is caused by the JC virus in the setting of chronic immune deficiency. Developing therapy has been challenged by the rarity of the disease as well as the complexity of patients in whom it develops. Several small trials directed at presumptive antiviral therapies have failed to show convincing clinical ...
openaire   +3 more sources

Multifocal laser direct writing through spatial light modulation guided by scalable vector graphics [PDF]

arXiv, 2023
Multifocal laser direct writing (LDW) based on phase-only spatial light modulator (SLM) can realize flexible and parallel nanofabrication with high throughput potential. In this investigation, a novel approach of combining two-photon absorption, SLM and vector path guided by scalable vector graphics (SVG) has been developed and tested preliminarily ...
arxiv  

High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]

, 2011
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG, Cao, Q, Green, KG, Jacobson, PA, Long-Boyle, JR, McGlave, PB, Miller, JS, Rogosheske, J, Wagner, JE, Weisdorf, DJ   +9 more
core   +1 more source