Results 141 to 150 of about 33,332 (299)
Calibration of multisite raters for prospective visual reads of amyloid PET scans
Abstract INTRODUCTION In multicenter Alzheimer's disease studies, amyloid positron emission tomography (PET) visual reads are typically performed centrally by a few experts. Incorporating a broader reader network enhances scalability and generalizability.
David N. Soleimani‐Meigooni +24 more
wiley +1 more source
Subcortical dementia and competency: Two cases of progressive supranuclear palsy [PDF]
Jordyn Rice +3 more
openalex +1 more source
Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers
Abstract Our understanding of Alzheimer's disease (AD) and related dementias (ADRD) has grown exponentially, thanks to significant investments by the National Institute on Aging (NIA). This article celebrates the 40th anniversary of the NIA's Alzheimer's Disease Research Centers, highlighting the pivotal role of neuropathology as the bedrock for ...
D. Luke Fischer +45 more
wiley +1 more source
J C Steele's reflections on progressive supranuclear palsy. [PDF]
J. Pearce
openalex +1 more source
Abstract INTRODUCTION Distinguishing behavioral variant frontotemporal dementia (bvFTD) from primary psychiatric disorders (PPDs) remains challenging due to overlapping clinical presentation. Neurofilament light chain (NfL) is a biomarker of neuronal damage that is elevated in neurodegenerative diseases. This study assessed the effectiveness of NfL and
Sean Coulborn +18 more
wiley +1 more source
Lipoperoxidation Is Selectively Involved in Progressive Supranuclear Palsy [PDF]
Patrizio Odetti +12 more
openalex +1 more source
Abstract BACKGROUND This study assessed the impact of cerebral small vessel disease (CSVD) on cognition in individuals with early‐onset (EO; <65 years) and late‐onset (LO; ≥65 years) cognitive complaints. METHODS Participants underwent prospective evaluations including cognitive testing, hyperphosphorylated tau‐217 (p‐tau217) and neurofilament‐light ...
Jonathan Naftali +9 more
wiley +1 more source
Abstract INTRODUCTION Machine learning (ML) is increasingly used for clinical classification of Alzheimer's disease (AD) and related dementias. Prior studies identified useful diagnostic features for AD and behavioral variant frontotemporal dementia (bvFTD), though they often lack pathological verification.
Grace J. Goodwin +4 more
wiley +1 more source
Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles
A. Probst +5 more
openalex +2 more sources
Loss of thalamic intralaminar nuclei in progressive supranuclear palsy and Parkinson's disease: clinical and therapeutic implications [PDF]
J. M. Henderson
openalex +1 more source

