Results 141 to 150 of about 33,332 (299)

Calibration of multisite raters for prospective visual reads of amyloid PET scans

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION In multicenter Alzheimer's disease studies, amyloid positron emission tomography (PET) visual reads are typically performed centrally by a few experts. Incorporating a broader reader network enhances scalability and generalizability.
David N. Soleimani‐Meigooni   +24 more
wiley   +1 more source

Subcortical dementia and competency: Two cases of progressive supranuclear palsy [PDF]

open access: bronze, 1997
Jordyn Rice   +3 more
openalex   +1 more source

Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract Our understanding of Alzheimer's disease (AD) and related dementias (ADRD) has grown exponentially, thanks to significant investments by the National Institute on Aging (NIA). This article celebrates the 40th anniversary of the NIA's Alzheimer's Disease Research Centers, highlighting the pivotal role of neuropathology as the bedrock for ...
D. Luke Fischer   +45 more
wiley   +1 more source

Combining plasma neurofilament light chain and frontotemporal atrophy improves differentiation of bvFTD from primary psychiatric disorders

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Distinguishing behavioral variant frontotemporal dementia (bvFTD) from primary psychiatric disorders (PPDs) remains challenging due to overlapping clinical presentation. Neurofilament light chain (NfL) is a biomarker of neuronal damage that is elevated in neurodegenerative diseases. This study assessed the effectiveness of NfL and
Sean Coulborn   +18 more
wiley   +1 more source

Lipoperoxidation Is Selectively Involved in Progressive Supranuclear Palsy [PDF]

open access: bronze, 2000
Patrizio Odetti   +12 more
openalex   +1 more source

Impact of cerebral small vessel disease on cognitive outcomes in early age at onset MCI and dementia: Findings from the DIASPORA study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract BACKGROUND This study assessed the impact of cerebral small vessel disease (CSVD) on cognition in individuals with early‐onset (EO; <65 years) and late‐onset (LO; ≥65 years) cognitive complaints. METHODS Participants underwent prospective evaluations including cognitive testing, hyperphosphorylated tau‐217 (p‐tau217) and neurofilament‐light ...
Jonathan Naftali   +9 more
wiley   +1 more source

Classification of AD and bvFTD using neuropsychological and neuropsychiatric variables: a machine learning study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Machine learning (ML) is increasingly used for clinical classification of Alzheimer's disease (AD) and related dementias. Prior studies identified useful diagnostic features for AD and behavioral variant frontotemporal dementia (bvFTD), though they often lack pathological verification.
Grace J. Goodwin   +4 more
wiley   +1 more source

Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles

open access: green, 1988
A. Probst   +5 more
openalex   +2 more sources

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