Results 1 to 10 of about 30,866 (234)
Progressive Supranuclear Palsy [PDF]
Parkinsonism & Related Disorders, 2012 Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy which can manifest clinically in a variety of syndromes. In this review, the classic and most common variant syndrome -PSP-Richardson's syndrome (PSP-RS) -is the focus, with the core clinical features, varying cognitive/motor/neuropsychiatric/sleep manifestations, neuropsychological ...
Hoelzle, James B
core +8 more sources
Progressive supranuclear palsy: new concepts [PDF]
Arquivos de Neuro-Psiquiatria, 2010 Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia.
Orlando Graziani Povoas Barsottini +3 more
doaj +5 more sources
Progressive supranuclear palsy [PDF]
Seminars in Neurology, 2001 Unfortunately, no drug treatment has been shown to benefit patients with progressive supranuclear palsy (PSP) more than modestly or briefly. The multiplicity of neuronal systems and synaptic physiologies that degenerate in this disorder makes a neurotransmitter-specific approach, such as neurotransmitter replacement or reuptake inhibition, unlikely to ...
K, Tawana, D B, Ramsden
openaire +5 more sources
Progressive supranuclear palsy [PDF]
Postgraduate Medical Journal, 2000 Abstract Progressive supranuclear palsy (PSP) or Steele-Richardson-Olszewski syndrome is a neurodegenerative disease of middle and late age. It is under-diagnosed not only by general physicians but also by neurologists. The cause of PSP is not known.
, Lowrey, , Wong
openaire +4 more sources
Clinical Features of Patients With Progressive Supranuclear Palsy in an US Insurance Claims Database
Frontiers in Neurology, 2021 Background: Progressive supranuclear palsy is a rare neurodegenerative movement disorder and little is known about its epidemiology.Objective: Estimate age-adjusted prevalence of progressive supranuclear palsy and describe antecedent diagnoses and ...
Emma Viscidi +11 more
doaj +1 more source
Journal of Medical Case Reports, 2021 Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy.
Huiping Li +7 more
doaj +1 more source
Neuroimaging correlates of gait abnormalities in progressive supranuclear palsy
NeuroImage: Clinical, 2021 Progressive supranuclear palsy is a neurodegenerative disorder characterized primarily by tau inclusions and neurodegeneration in the midbrain, basal ganglia, thalamus, premotor and frontal cortex.
Irene Sintini +12 more
doaj +1 more source
Diagnostics, 2022 Progressive supranuclear palsy syndrome (PSPS) and corticobasal syndrome (CBS) are clinical manifestations of tauopathic Parkinsonian syndromes. Due to their overlapping symptomatology, the differential diagnosis of these entities may be difficult when ...
Piotr Alster +6 more
doaj +1 more source
Progressive supranuclear palsy
Hospital Medicine, 2003 Progressive supranuclear palsy, also known as Steele–Richardson–Olszewski syndrome, is an uncommon neurodegenerative parkinsonian disorder that starts in middle and late life, and is frequently misdiagnosed as Parkinson's disease. This review will cover the epidemiology, clinical picture, differential diagnosis and management of patients with ...
Douglas G. Cole, Nutan Sharma
+5 more sources
Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]
, 2017 Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo +9 more
core +2 more sources