Results 41 to 50 of about 743,600 (215)

Progressive supranuclear palsy: new concepts

Arquivos de Neuro-Psiquiatria, 2010
Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia.
Orlando Graziani Povoas Barsottini, André Carvalho Felício, Camila Catherine Henriques de Aquino, José Luiz Pedroso   +3 more
doaj   +1 more source

Progressive Supranuclear Gaze Palsy with Predominant Cerebellar Ataxia: A Case Series with Videos [PDF]

Journal of Movement Disorders, 2017
Progressive supranuclear palsy (PSP) with predominant cerebellar ataxia (PSP-C) is a rare phenotype of PSP. The clinical and radiological features of this disorder remain poorly characterized.
Zheyu Xu, Tchoyoson C.C. Lim, Wing Lok Au, Louis C.S. Tan   +3 more
doaj   +1 more source

REM sleep behavior in Parkinson disease: Frequent, particularly with higher age.

PLoS ONE, 2020
This retrospective single-center polysomnography-based study was designed to assess the frequency of REM sleep behavior disorder (RBD) in consecutive patients with Parkinsonism, including Parkinson disease, dementia with Lewy bodies, multiple system ...
Heide Baumann-Vogel, Hyun Hor, Rositsa Poryazova, Philipp Valko, Esther Werth, Christian R Baumann   +5 more
doaj   +1 more source

Clinical Approach to Progressive Supranuclear Palsy [PDF]

Journal of Movement Disorders, 2016
Sixty years ago, Steele, Richardson and Olszewski designated progressive supranuclear palsy (PSP) as a new clinicopathological entity in their seminal paper. Since then, in addition to the classic Richardson’s syndrome (RS), different clinical phenotypic
Helen Ling
doaj   +1 more source

Progressive Supranuclear Palsy with Predominant Cerebellar Ataxia [PDF]

Journal of Movement Disorders, 2020
Progressive supranuclear palsy (PSP) is characterized by supranuclear gaze palsy, dystonic rigidity of the neck and upper trunk, frequent falls and mild cognitive impairment.
Shoichiro Ando, Masato Kanazawa, Osamu Onodera   +2 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

The Effectiveness of Exercise Programs on Balance, Functional Ability, Quality of Life, and Depression in Progressive Supranuclear Palsy: A Case Study

Applied Sciences
Progressive supranuclear palsy is a form of atypical Parkinsonism. People living with Progressive Supranuclear Palsy have various symptoms, such as movement and cognitive disorders, which mainly affect balance and functional ability with an increased ...
Panagiotis Papamichail, Michail Michalas, Dimitris Krokos, Maria Balamoutsou, Panagiota Karkoula, Epameinondas Lyros, Vasiliki Sakellari, Anna Christakou   +7 more
doaj   +1 more source

DISSOCIATION OF CLINICAL MANIFESTATIONS AND NEUROIMAGING IN PROGRESSIVE SUPRANUCLEAR PALSY (PAIRED CLINICAL CASE OF STEELE-RICHARDSON-OLSHEVSKY SYNDROME)

Байкальский медицинский журнал
Relevance. The differential diagnosis of motor neuron diseases is very difficult in practical medical practice. Early diagnosis of this group of diseases, in particular, progressive supranuclear palsy, is of particular importance.
Yury N. Bykov, Elena I. Panferova, Tatiana N. Zagvozkina, Iuliia A. Skvortsova, Arina V. Shirokova   +4 more
doaj   +1 more source

Apraxia in progressive nonfluent aphasia [PDF]

, 2010
The clinical and neuroanatomical correlates of specific apraxias in neurodegenerative disease are not well understood. Here we addressed this issue in progressive nonfluent aphasia (PNFA), a canonical subtype of frontotemporal lobar degeneration that has
Rohrer, J.D., Rossor, M.N., Warren, J.D.
core  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source