Results 51 to 60 of about 16,224 (212)

FXTAS and the Spectrum of FMR1 Premutation‐Associated Phenotypes in Latin America: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative disorder caused by FMR1 premutation expansions (55–200 CGG repeats). Although well described in populations of predominantly European ancestry, FXTAS remains poorly characterized in Latin America due to limited awareness, restricted access to ...
Amy Schmidmajer, Salomón Páez‐García, Santiago Martínez, Jacobo Ramírez‐Triana, Kevin O'Hara‐Veintimilla, Andrés Ricaurte‐Fajardo, Catalina Cerquera‐Cleves   +6 more
wiley   +1 more source

Progressive supranuclear palsy

Hospital Medicine, 2003
Progressive supranuclear palsy, also known as Steele–Richardson–Olszewski syndrome, is an uncommon neurodegenerative parkinsonian disorder that starts in middle and late life, and is frequently misdiagnosed as Parkinson's disease. This review will cover the epidemiology, clinical picture, differential diagnosis and management of patients with ...
openaire   +2 more sources

Pilot Study of [¹¹C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer

Cells
A novel brain positron emission tomography (PET) radioligand, [11C]HY-2-15, has potential for imaging alpha-synuclein aggregations in multiple system atrophy and misfolded tau proteins in tauopathies, based on its high binding affinity in disease brain ...
Chia-Ju Hsieh, Dinahlee Saturnino Guarino, Anthony J. Young, Andrew D. Siderowf, Ilya Nasrallah, Alexander Schmitz, Carol Garcia, Ho Young Kim, Erin K. Schubert, Hsiaoju Lee, Joel S. Perlmutter, Robert H. Mach   +11 more
doaj   +1 more source

Progressive supranuclear palsy: A systematic review

Neurobiology of Disease, 2005
The progressive supranuclear palsy (PSP) is a rapidly progressing degenerative disease belonging to the family of tauophaties, characterized by the involvement of both cortical and subcortical structures.
L. Rampello, V. Buttà, R. Raffaele, I. Vecchio, G. Battaglia, G. Cormaci, A. Alvano   +6 more
doaj   +1 more source

Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Continuous subcutaneous apomorphine infusion (CSAI) is effective in Parkinson's disease but has not been evaluated in multiple system atrophy (MSA). Objective To assess the 6‐month efficacy and tolerability of CSAI in MSA patients. Methods French multicenter retrospective registry‐based analysis of CSAI use in MSA.
Simon Lamy, Frederique Leh, Alexandra Foubert‐Samier, Soizic Leguy Bonnet, Guillaume Baille, Margherita Fabbri, Margaux Dunoyer, Lise Mantisi, Caroline Giordana, Anaïs El Ouartassi, Olivier Rascol, Wassilios G. Meissner, David Bendetowicz, Marie Vanel, David Grabli, Fabienne Ory‐Magne, Sophie Drapier   +16 more
wiley   +1 more source

Pyramidal system involvement in progressive supranuclear palsy – a clinicopathological correlation

BMC Neurology, 2019
Background We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).
Zuzana Stejskalova, Zdenek Rohan, Robert Rusina, Adam Tesar, Jaromir Kukal, Gabor G. Kovacs, Ales Bartos, Radoslav Matej   +7 more
doaj   +1 more source

Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fracture risk is increased in Parkinson's yet this risk is often not addressed. Objectives Our objective was to study the extent to which osteoporosis was treated, and predictors of treatment in a large representative cohort with parkinsonism.
Katie C. Naylor, Emily J. Henderson, Emma Tenison   +2 more
wiley   +1 more source

Corticobasal degeneration and corticobasal syndrome: A review

Clinical Parkinsonism & Related Disorders, 2019
Corticobasal degeneration (CBD) is a rare neurodegenerative disorder. The most common presentation of CBD is the corticobasal syndrome (CBS), which is a constellation of cortical and extrapyramidal symptoms and signs.
Vasilios C. Constantinides, George P. Paraskevas, Panagiotis G. Paraskevas, Leonidas Stefanis, Elisabeth Kapaki   +4 more
doaj   +1 more source

Enteral Nutrition in Idiopathic Parkinson's Disease and Atypical Parkinsonism: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dysphagia and malnutrition are common in advanced Parkinson's disease and atypical parkinsonism. There is a lack of evidence to guide the use of enteral nutrition in these situations, including whether it improves survival or reduces aspiration pneumonia.
Bradley Lonergan, Matteo Ciocca, Anette Schrag, Yen Tai   +3 more
wiley   +1 more source

Frontrunner in Translation: Progressive Supranuclear Palsy

Frontiers in Neurology, 2019
Progressive supranuclear palsy (PSP) is a four-repeat tau proteinopathy. Abnormal tau deposition is not unique for PSP and is the basic pathologic finding in some other neurodegenerative disorders such as Alzheimer's disease (AD), age-related tauopathy ...
Ali Shoeibi, Nahid Olfati, Irene Litvan
doaj   +1 more source