Results 71 to 80 of about 16,179 (202)
4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy
Nature CommunicationsProgressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by abnormal accumulation of the protein tau in the brain, leading to motor and cognitive symptoms that vary between individuals. The reasons for this clinical heterogeneity
Ivan Martinez-Valbuena +21 more
doaj +1 more source
Cardiac MIBG Scintigraphy in Neurodegenerative Parkinsonism: Limitations in Clinical Practice
Movement Disorders Clinical Practice, EarlyView.Abstract Background Reduced cardiac uptake on 123Iodine‐metaiodobenzylguanidine (MIBG) scintigraphy is a valuable tool for differentiating neurodegenerative parkinsonism but interpretation can be difficult due to comorbidities and drug‐tracer interactions.
Frank Jagusch +9 more
wiley +1 more source
Progressive Supranuclear Palsy Syndrome: An Overview
IBRO Neuroscience ReportsProgressive supranuclear palsy (PSP) is a neurodegenerative disease, commonly observed as a movement disorder in the group of parkinsonian diseases. The term PSP usually refers to PSP-Richardson’s syndrome (PSP-RS), the most typical clinical presentation.
Eduardo Ichikawa-Escamilla +2 more
doaj +1 more source
Challenges with the differential diagnosis of progressive supranuclear palsy and Parkinson’s disease
Анналы клинической и экспериментальной неврологии, 2017 Progressive supranuclear palsy (PSP) is a severe old-age neurodegenerativedisease that is characterized by pronouncedclinical polymorphism and has different phenotypes.
R. V. Magzhanov +5 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Background Progressive supranuclear palsy (PSP) is a rare and devastating tauopathy with limited global data. Given India's large population, genetic diversity, and clinical heterogeneity, large multicenter datasets are crucial to enrich global understanding of PSP. Objective To characterize the demographic, clinical, and phenotypic profiles of a large
Prashanth Lingappa Kukkle +31 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero +12 more
wiley +1 more source
Reversible drug-induced progressive supranuclear palsy-like presentation: A report of three cases
Annals of Movement Disorders, 2019 Drugs, such as dopamine receptor blockers or dopamine depleters, produce a functional dopamine-deficient state mimicking parkinsonism, but presentation with a progressive supranuclear palsy (PSP) is a rare manifestation.
Shivani Rath, Deepika Joshi
doaj +1 more source
Movement Disorders, EarlyView.Abstract Background Emerging evidence implicates neuroinflammation in progressive supranuclear palsy (PSP) pathophysiology, with elevated cyto‐chemokines suggesting natural killer (NK) cell involvement. Methods We characterized peripheral NK in PSP (N = 11) versus Parkinson's disease (PD, N = 10) and healthy controls (HC, N = 8) at both ...
Marina Picillo +11 more
wiley +1 more source
Research on progressive supranuclear palsy
Chinese Journal of Contemporary Neurology and Neurosurgery, 2011 DOI：10.3969/j.issn.1672-6731.2011.01 ...
Yiming LIU, Jiazhen LI
doaj
Unilateral Freezing of Gait in Normal Pressure Hydrocephalus after Stroke
Movement Disorders Clinical Practice, EarlyView.
Jose Portales +2 more
wiley +1 more source