Results 21 to 30 of about 743,600 (215)

Progressive supranuclear palsy [PDF]

Postgraduate Medical Journal, 2000
Abstract Progressive supranuclear palsy (PSP) or Steele-Richardson-Olszewski syndrome is a neurodegenerative disease of middle and late age. It is under-diagnosed not only by general physicians but also by neurologists. The cause of PSP is not known.
, Lowrey, , Wong
openaire   +4 more sources

The Progressive Supranuclear Palsy Clinical Deficits Scale

, 2020
Background: There is currently no undisputed, validated, clinically meaningful measure for deficits in the broad spectrum of PSP phenotypes. Objective: To develop a scale to monitor clinical deficits in patients with PSP across its broad phenotypes ...
Stebbins, G.T., ProPSP study group, Goetz, C.G., Sckopke, P., Stamelou, M., DescribePSP study group, Höglinger, G.U., Piot, I., Schweyer, K., Schenk, T., Respondek, G., MDS-endorsed PSP study group   +11 more
core   +5 more sources

Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report

Journal of Medical Case Reports, 2021
Background Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy.
Huiping Li, Fang Yuan, Yaming Du, Tao Pan, Wanxin Wen, Shaoxue Li, Lixin Wang, Aili Lu   +7 more
doaj   +1 more source

Global Rather Than Vertical-Selective Saccadic Abnormalities in Progressive Supranuclear Palsy. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Nguyen DD, Paine M, Lee S, Fazlollahi A, Wang BB, O'Sullivan JD, Nestor PJ.   +6 more
europepmc   +2 more sources

Neuroimaging correlates of gait abnormalities in progressive supranuclear palsy

NeuroImage: Clinical, 2021
Progressive supranuclear palsy is a neurodegenerative disorder characterized primarily by tau inclusions and neurodegeneration in the midbrain, basal ganglia, thalamus, premotor and frontal cortex.
Irene Sintini, Kenton Kaufman, Hugo Botha, Peter R. Martin, Stacy R. Loushin, Matthew L. Senjem, Robert I. Reid, Christopher G. Schwarz, Clifford R. Jack Jr, Val J. Lowe, Keith A. Josephs, Jennifer L. Whitwell, Farwa Ali   +12 more
doaj   +1 more source

Cognitive, Motor and Oculomotor Contributions to the Trail Making Test in Progressive Supranuclear Palsy. [PDF]

Mov Disord Clin Pract
Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Garcia-Cordero I, Hadian M, Vargas-Gonzalez JC, Monteiro M, Gold D, Khoja A, Morales-Rivero A, Couto B, Tang-Wai D, Fox S, Kovacs GG, Lang AE, Tartaglia MC.   +12 more
europepmc   +2 more sources

Diplopia in Progressive Supranuclear Palsy [PDF]

Movement Disorders Clinical Practice, 2020
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Narges, Yazdi, Mona Ramezani, Ghamsari, Ali, Shoeibi, Mohammad, Rohani   +3 more
openaire   +2 more sources

The Significance of Asymmetry in the Assessment of Brain Perfusion in Atypical Tauopathic Parkinsonian Syndromes

Diagnostics, 2022
Progressive supranuclear palsy syndrome (PSPS) and corticobasal syndrome (CBS) are clinical manifestations of tauopathic Parkinsonian syndromes. Due to their overlapping symptomatology, the differential diagnosis of these entities may be difficult when ...
Piotr Alster, Natalia Madetko, Bartosz Migda, Michał Nieciecki, Michał Kutyłowski, Leszek Królicki, Andrzej Friedman   +6 more
doaj   +1 more source

9.4 T MR microscopy of the substantia nigra with pathological validation in controls and disease

NeuroImage: Clinical, 2017
Background: The anatomy of the substantia nigra on conventional MRI is controversial. Even using histological techniques it is difficult to delineate with certainty from surrounding structures.
LA Massey, MA Miranda, O Al-Helli, HG Parkes, JS Thornton, P-W So, MJ White, L Mancini, C Strand, J Holton, AJ Lees, T Revesz, TA Yousry   +12 more
doaj   +1 more source

Tremor in progressive supranuclear palsy [PDF]

Parkinsonism & Related Disorders, 2016
Tremor is thought to be a rare feature of progressive supranuclear palsy (PSP).We retrospectively reviewed the database of the CurePSP brain bank at Mayo Clinic Florida to retrieve all available clinical information for PSP patients. All patients underwent a standard neuropathological assessment and an immunohistochemical evaluation for tau and α ...
Shinsuke Fujioka, Avi A. Algom, Melissa E. Murray, Monica Y. Sanchez-Contreras, Pawel Tacik, Yoshio Tsuboi, Jay A. Van Gerpen, Ryan J. Uitti, Rosa Rademakers, Owen A. Ross, Zbigniew K. Wszolek, Dennis W. Dickson   +11 more
openaire   +2 more sources