Results 21 to 30 of about 34,892 (272)

Genetics of Progressive Supranuclear Palsy [PDF]

Journal of Movement Disorders, 2015
Progressive supranuclear palsy (PSP) is a neurodegenerative syndrome that is clinically characterized by progressive postural instability, supranuclear gaze palsy, parkinsonism and cognitive decline.
Sun Young Im, Young Eun Kim, Yun Joong Kim   +2 more
doaj   +1 more source

Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy.

PLoS ONE, 2019
Radiological biomarkers have been reported for multiple system atrophy and progressive supranuclear palsy, but serum/plasma biomarkers for each disorder have not been established.
Akio Mori, Kei-Ichi Ishikawa, Shinji Saiki, Taku Hatano, Yutaka Oji, Ayami Okuzumi, Motoki Fujimaki, Takahiro Koinuma, Shin-Ichi Ueno, Yoko Imamichi, Nobutaka Hattori   +10 more
doaj   +1 more source

A longitudinal study of motor, oculomotor and cognitive function in progressive supranuclear palsy.

PLoS ONE, 2013
ObjectiveWe studied the annual change in measures of motor, oculomotor and cognitive function in progressive supranuclear palsy. This had twin objectives, to assess the potential for clinical parameters to monitor disease progression in clinical trials ...
Boyd C P Ghosh, Roger H S Carpenter, James B Rowe   +2 more
doaj   +1 more source

Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]

, 2018
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele, Berardelli, Isabella, Fabbrini, Andrea, Fabbrini, Giovanni, Pasquini, Massimo, Pompili, Maurizio, Suppa, Antonio   +6 more
core   +1 more source

18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy. [PDF]

, 2016
The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these tauopathies and clinical trials of disease-modifying therapies.
Aigbirhio, Franklin I, Allinson, Kieren SJ, Arnold, Robert, Bevan-Jones, W Richard, Borchert, Robin J, Cope, Thomas E, Fryer, Tim D, Hong, Young T, Jones, P Simon, Mak, Elijah, O'Brien, John T, Passamonti, Luca, Rowe, James B, Sami, Saber, Su, Li, Surendranathan, Ajenthan, Vázquez Rodríguez, Patricia, Williamson, David   +17 more
core   +1 more source

Comparison of gait in progressive supranuclear palsy, Parkinson’s disease and healthy older adults

BMC Neurology, 2012
Background Progressive supranuclear palsy and Parkinson’s disease have characteristic clinical and neuropathologic profiles, but also share overlapping clinical features. This study aimed to analyze the gait of people with progressive supranuclear palsy (
Egerton Thorlene, Williams David R, Iansek Robert   +2 more
doaj   +1 more source

Clinical features of progressive supranuclear palsy

Frontiers in Aging Neuroscience, 2023
BackgroundProgressive supranuclear palsy (PSP) is a clinically heterogenous atypical parkinsonian syndrome. Therefore, early recognition and correct diagnosis of PSP is challenging but essential.
Yafei Wen, Qijie Yang, Bin Jiao, Bin Jiao, Bin Jiao, Bin Jiao, Bin Jiao, Weiwei Zhang, Jingyi Lin, Yuan Zhu, Qian Xu, Qian Xu, Hui Zhou, Ling Weng, Ling Weng, Xinxin Liao, Yafang Zhou, Junling Wang, Jifeng Guo, Jifeng Guo, Jifeng Guo, Jifeng Guo, Xinxiang Yan, Xinxiang Yan, Xinxiang Yan, Xinxiang Yan, Hong Jiang, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang, Lu Shen, Lu Shen, Lu Shen, Lu Shen, Lu Shen, Lu Shen   +36 more
doaj   +1 more source

Atypical parkinsonism: An Update. [PDF]

, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source

Accuracy of MR markers for differentiating Progressive Supranuclear Palsy from Parkinson's disease

NeuroImage: Clinical, 2016
Background: Advanced brain MR techniques are useful tools for differentiating Progressive Supranuclear Palsy from Parkinson's disease, although time-consuming and unlikely to be used all together in routine clinical work.
Stefano Zanigni, Giovanna Calandra-Buonaura, David Neil Manners, Claudia Testa, Dino Gibertoni, Stefania Evangelisti, Luisa Sambati, Maria Guarino, Patrizia De Massis, Laura Ludovica Gramegna, Claudio Bianchini, Paola Rucci, Pietro Cortelli, Raffaele Lodi, Caterina Tonon   +14 more
doaj   +1 more source

Methods and utility of quantitative brainstem measurements in progressive supranuclear palsy versus Parkinson's disease in a routine clinical setting

Clinical Parkinsonism & Related Disorders, 2020
Background and Purpose: The clinical diagnosis of progressive supranuclear palsy can be challenging, as the clinical presentation overlaps with that of Parkinson's disease and multiple system atrophy.
Jessica Cooperrider, Brent Bluett, Stephen E. Jones   +2 more
doaj   +1 more source