Intrinsic connectivity network disruption in progressive supranuclear palsy [PDF]
Objective Progressive supranuclear palsy (PSP) has been conceptualized as a large-scale network disruption, but the specific network targeted has not been fully characterized.
Boxer, Adam L. +11 more
core +1 more source
Progressive supranuclear palsy: A systematic review
The progressive supranuclear palsy (PSP) is a rapidly progressing degenerative disease belonging to the family of tauophaties, characterized by the involvement of both cortical and subcortical structures.
L. Rampello +6 more
doaj +1 more source
The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons [PDF]
Frontotemporal lobar degeneration (FTLD) consists of a group of neurodegenerative diseases characterized by behavioural and executive impairment, language disorders and motor dysfunction.
Calo, Laura +14 more
core +4 more sources
Voice and Speech in Atypical Parkinsonian Disorders
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel +48 more
wiley +1 more source
PET-CT imaging in a patient with progressive supranuclear palsy [PDF]
Hosp Beneficencia Portuguesa São Paulo, Med Imagem, BR-01323001 São Paulo, SP, BrazilUniversidade Federal de São Paulo, Dept Neurol, São Paulo, SP, BrazilHosp Coracao, São Paulo, SP, BrazilUniversidade Federal de São Paulo, Dept Neurol, São Paulo, SP ...
Amaral, Lazaro Luiz Faria do +6 more
core +2 more sources
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner +10 more
wiley +1 more source
Corticobasal degeneration and corticobasal syndrome: A review
Corticobasal degeneration (CBD) is a rare neurodegenerative disorder. The most common presentation of CBD is the corticobasal syndrome (CBS), which is a constellation of cortical and extrapyramidal symptoms and signs.
Vasilios C. Constantinides +4 more
doaj +1 more source
Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons [PDF]
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by the presence of intracellular aggregates of tau protein and neuronal loss leading to cognitive and motor impairment.
Alquezar, Carolina +7 more
core +2 more sources
Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia [PDF]
PURPOSE: There are no comprehensive guidelines for the use of FDG PET in the following three clinical scenarios: (1) diagnostic work-up of patients with idiopathic Parkinson's disease (PD) at risk of future cognitive decline, (2) discriminating ...
Agosta, F +13 more
core +1 more source
Longitudinal Videofluorographic Dysphagia Measures in Progressive Supranuclear Palsy
Abstract Background Dysphagia can lead to fatal aspiration pneumonia in progressive supranuclear palsy (PSP). Little is known about the longitudinal progression of dysphagia or whether it differs across PSP clinical variants. Objectives To characterize longitudinal changes in dysphagia across PSP variants and determine relationships with disease ...
Anna Chiara Cattani +8 more
wiley +1 more source

