Advanced Science, EarlyView.The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He +9 more
wiley +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Evaluation of dystrophic calcification in juvenile dermatomyositis and systemic sclerosis
Acta Pediátrica de México, 2014 Background: Dystrophic calcification is associated with juvenile dermatomyositis and progressive systemic sclerosis. The clinical diagnosis is established with detection of subcutaneous and petrous nodules.
Marimar Saez-de Ocariz
doaj +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Copeptin as a Biomarker of Microcirculation Alterations in Systemic Sclerosis
Clinical, Cosmetic and Investigational Dermatology, 2023 Magdalena Maciejewska,1 Albert Stec,2 Michał Zaremba,2 Cezary Maciejewski,3 Lidia Rudnicka,2 Mariusz Sikora4 1Department of Dermatology, Doctoral School of Medical University of Warsaw, Warsaw, Poland; 2Department of Dermatology, Medical ...
Maciejewska M +5 more
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Serum interleukin-6 level and its association with pulmonary involvement in progressive systemic sclerosis; a case-control study. [PDF]
Clin Mol Allergy, 2023 Piroozmand A +3 more
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Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis
Advanced Science, EarlyView.Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart +4 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
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Progressive Systemic Sclerosis With Negative Antinuclear Antibodies and Absence of Raynaud's Phenomenon: A Case Report and Literature Review. [PDF]
Cureus, 2023 Falls AC, Wrigley C, Khanna SA.
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Leukocyte migration inhibition in progressive systemic sclerosis [PDF]
, 1974 Pamela Hughes, Shirley Holt, N.R. Rowell
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