Redox Biology, 2019 Systemic sclerosis is an autoimmune disorder characterized by inflammation and a progressive fibrosis affecting the skin and visceral organs. Over the last two decades, it became clear that oxidative stress plays a key role in its pathogenesis.
Ludivine Doridot +3 more
doaj
Global well-posedness and nonlinear stability of a chemotaxis system modeling multiple sclerosis [PDF]
arXiv, 2020 We consider a system of reaction-diffusion equations including chemotaxis terms and coming out of the modeling of multiple sclerosis. The global existence of strong solutions to this system in any dimension is proved, and it is also shown that the solution is bounded uniformly in time.
arxiv
Cuproplasia and cuproptosis, two sides of the coin
Cancer Communications, EarlyView.Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu +4 more
wiley +1 more source
The efficacy of PDE5 inhibitors in diabetic patients
Andrology, Volume 11, Issue 2, Page 245-256, February 2023., 2023 Abstract Background Phosphodiesterase 5 inhibitors (PDE5i), since their introduction in the late 1990s, have proven their efficacy in treating several conditions, predominantly pulmonary hypertension and erectile dysfunction where they remain the first‐line therapeutic option.
Agnieszka Swiecicka
wiley +1 more source
Multiple Sclerosis Lesion Segmentation from Brain MRI via Fully Convolutional Neural Networks [PDF]
arXiv, 2018 Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white matter. Quantitative measures based on various features of lesions have been shown to be useful in clinical trials for ...
arxiv
Contemporary Perspectives on Chronic Renal Disorders
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok +5 more
wiley +1 more source
Evaluation of dystrophic calcification in juvenile dermatomyositis and systemic sclerosis
Acta Pediátrica de México, 2014 Background: Dystrophic calcification is associated with juvenile dermatomyositis and progressive systemic sclerosis. The clinical diagnosis is established with detection of subcutaneous and petrous nodules.
Marimar Saez-de Ocariz
doaj +1 more source
Serum interleukin-6 level and its association with pulmonary involvement in progressive systemic sclerosis; a case-control study. [PDF]
Clin Mol Allergy, 2023 Piroozmand A +3 more
europepmc +1 more source
Copeptin as a Biomarker of Microcirculation Alterations in Systemic Sclerosis
Clinical, Cosmetic and Investigational Dermatology, 2023 Magdalena Maciejewska,1 Albert Stec,2 Michał Zaremba,2 Cezary Maciejewski,3 Lidia Rudnicka,2 Mariusz Sikora4 1Department of Dermatology, Doctoral School of Medical University of Warsaw, Warsaw, Poland; 2Department of Dermatology, Medical ...
Maciejewska M +5 more
doaj
Progressive Systemic Sclerosis With Negative Antinuclear Antibodies and Absence of Raynaud's Phenomenon: A Case Report and Literature Review. [PDF]
Cureus, 2023 Falls AC, Wrigley C, Khanna SA.
europepmc +1 more source