Results 101 to 110 of about 769,984 (331)

Lamellarin D Acts as an Inhibitor of Type I Collagen Production

ChemMedChem, EarlyView.
COL1A2 gene, encoding type I collagen, is a key target for pulmonary fibrosis. We established a screening system to identify small molecules that inhibit COL1A2 gene expression. Using this system, we screen a library of compounds and identify lamellarin D as a potent inhibitor of COL1A2 expression, suggesting lamellarin D is a promising new lung ...
Daisuke Okuno, Noriho Sakamoto, Hideki Hayashi, Tsutomu Fukuda, Yoshiko Akiyama, Chiaki Iketani, Ritsuko Murakami, Takatomo Tokito, Takuto Miyamura, Hirokazu Yura, Takashi Kido, Hiroshi Ishimoto, Shinnosuke Takemoto, Takahiro Takazono, Tomoya Nishino, Yuji Ishimatsu, Jun Ishihara, Kohsuke Takeda, Yoshimasa Tanaka, Hiroshi Mukae   +19 more
wiley   +1 more source

Subcutaneous immunoglobulin therapy for refractory skin thickening in rapidly progressive systemic sclerosis: A case report and literature review. [PDF]

J Scleroderma Relat Disord, 2023
Cacciapaglia F, Stano S, Fornaro M, Iannone F.   +3 more
europepmc   +1 more source

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

Clinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang, Logan Brooks, Denise M. Boudreau, Pascal Chanu, Amita Joshi, Bianca Vora, Rui Zhu   +6 more
wiley   +1 more source

Scleroderma renal crisis in tropical region: two senegalese cases

The Pan African Medical Journal, 2015
Scleroderma renal crisis (SRC) is defined as the new onset of accelerated arterial hypertension and /or rapidly progressive oliguric renal failure during the course of systemic sclerosis. It is a rare but life-threatening complication.
Mouhamadou Moustapha Cisse, Sidy Mohamed Seck, Daher Abdoul Karim Oumar, Khodia Fall, Ahmed Tall Lemrabott, Moussa Diallo, Maria Faye, Moustapha Faye, Abdou Niang, Boucar Diouf   +9 more
doaj   +1 more source

Some Immunologic Considerations in Focal Scleroderma and Progressive Systemic Sclerosis in Children [PDF]

, 1974
Virgil Hanson, Helen Kornreich, Elizabeth Drexler, Gerald D. Johnson, G A MacPherson   +4 more
openalex   +1 more source

Assessing the Role of Volumetric Brain Information in Multiple Sclerosis Progression [PDF]

arXiv
Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions. Deformation-based morphometry utilizes anatomical magnetic resonance imaging to quantitatively assess volumetric brain ...
arxiv  

Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis

ESC Heart Failure, EarlyView.
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher, Roger Hodkinson, William Makis, Peter A. McCullough   +3 more
wiley   +1 more source

A case of progressive systemic sclerosis/lupus overlap syndrome: Presenting with parotid swelling. [PDF]

J Oral Maxillofac Pathol, 2021
Ramya R, Swarnalakshmi R, Preethi A, Pradeep R.   +3 more
europepmc   +1 more source

Progressive systemic sclerosis and autoimmune haemolytic anaemia [PDF]

, 1976
E. Sumithran
openalex   +1 more source

Longitudinal Missing Data Imputation for Predicting Disability Stage of Patients with Multiple Sclerosis [PDF]

arXiv
Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent approach might help in suggesting interventions that can delay the progression of the disease.
arxiv