Results 101 to 110 of about 929,362 (315)
Risk Prediction of a Multiple Sclerosis Diagnosis [PDF]
arXiv, 2013 Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to slow the disease progression and help manage symptoms, MS research has yet to result in a cure. Early diagnosis and
arxiv
A chemotaxis reaction-diffusion model for Multiple Sclerosis with Allee effect [PDF]
arXiv, 2023 In this paper, we study a modification of the mathematical model describing inflammation and demyelination patterns in the brain caused by Multiple Sclerosis proposed in [Lombardo et al. (2017), Journal of Mathematical Biology, 75, 373--417]. In particular, we hypothesize a minimal amount of macrophages to be able to start and sustain the inflammatory ...
arxiv
Strategies for anti-fibrotic therapies. [PDF]
, 2013 The fibrotic diseases encompass a wide spectrum of entities including such multisystemic diseases as systemic sclerosis, nephrogenic systemic fibrosis and sclerodermatous graft versus host disease, as well as organ-specific disorders such as pulmonary ...
Jimenez, Sergio A. +2 more
core +2 more sources
Autologous Fat Grafting in the Treatment of Facial Scleroderma
Dermatology Research and Practice, 2018 Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis. Orofacial manifestations of systemic sclerosis are extremely disabling and treatment options are limited.
Mehdi Gheisari +4 more
doaj +1 more source
Przegląd Dermatologiczny, 2017 Systemic sclerosis is an immune-mediated disease characterized by a chronic progressive course. The complex and diverse clinical features seen in patients require case-by-case approach and cooperation of multiple specialists both at the stage of ...
Dorota Krasowska +10 more
doaj +1 more source
A temporal model for multiple sclerosis course evolution [PDF]
arXiv, 2016 Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently investigating on the use of patient reported outcome measures for the assessment of impact and evolution of the disease on the
arxiv
On a chemotaxis model with nonlinear diffusion modelling multiple sclerosis [PDF]
arXiv, 2023 We investigated existence of global weak solutions for a system of chemotaxis type with nonlinear degenerate diffusion, arising in modelling Multiple Sclerosis disease. The model consists of three equations describing the evolution of macrophages ($m$), cytokine ($c$) and apoptotic oligodendrocytes ($d$). The main novelty in our work is the presence of
arxiv
Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]
, 2016 Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M +6 more
core +1 more source
Arthritis & Rheumatism, 1980 Antinuclear antibodies were demonstrated in the sera of 43 of 45 (96%) patients with progressive systemic sclerosis (22 of 24 with diffuse scleroderma and 21 of 21 with the CREST syndrome variant). This high percentage of positive reactions resulted from
E. Tan +6 more
semanticscholar +1 more source
Arthritis Research & Therapy, 2010 IntroductionAn over-expression of CD19 has been shown in B cells of systemic sclerosis (SSc) and B cells are thought to contribute to the induction of skin fibrosis in the tight skin mouse model. The aim was to define the outcome on safety and the change
S. Bosello +7 more
semanticscholar +1 more source